SynthesisInternational urology and nephrology2026
Impact of frailty on overall survival and complications in patients with prostate cancer: a systematic review and meta-analysis.
Synthesis in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Disproportionate expansion of radical prostatectomy among older men in Japan in the robotic surgery era: a nationwide descriptive time series analysis.Journal of robotic surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
purposeThe current systematic review and meta-analysis was designed to assess if the presence of frailty had an adverse impact on overall survival (OS) and complication rates of patients with prostate cancer.
methodsTwo reviewers explored the PubMed, Web of Science, Embase, and Scopus databases until January 3rd, 2026, for studies examining the impact of frailty on OS and complications in patients with prostate cancer. Data on OS were pooled as a hazard ratio (HR), while short-term mortality and complications were pooled as odds ratios (OR) in a random-effects model.
results13 studies with 173,378 patients were included. Pooled analysis showed that the presence of frailty was associated with a statistically significant increase in the risk of lower OS in prostate cancer patients (HR: 1.98, 95% CI 1.48, 2.63, I
conclusionsThe presence of frailty can lead to significantly lower OS and a higher risk of complications in patients with prostate cancer. Given the scarce data, the association between frailty and short-term mortality should be interpreted as exploratory.
Indexed as
Identifiers
41712034What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.