Evidence map›Paper›PMID 41712004›Full record

SynthesisEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2026

Revision and postoperative complication rates of conversion total hip arthroplasty after cephalomedullary nailing of intertrochanteric femur fractures: a systematic review and meta-analysis.

Harmon S Khela, Harsh Wadhwa, Henry J Wong, L Henry Goodnough

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Harmon S KhelaPerelman School of Medicine, University of Pennsylvania, Philadelphia, USA. harmon.khela@pennmedicine.upenn.edu.
Harsh WadhwaDepartment of Orthopaedic Surgery, Stanford Medicine, Stanford, USA.
Henry J WongDepartment of Orthopaedic Surgery, Stanford Medicine, Stanford, USA.
L Henry GoodnoughDepartment of Orthopaedic Surgery, Stanford Medicine, Stanford, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeManagement of failed intertrochanteric (IT) fracture fixation often requires conversion total hip arthroplasty (cTHA), but complication and reoperation rates remain poorly characterized in the literature. This study aimed to characterize revision and postoperative complication rates for cTHA after cephalomedullary nailing of IT fractures.

methodsA systematic review and meta-analysis was conducted following PRISMA guidelines. PubMed and Embase were queried for studies examining cTHA outcomes after prior cephalomedullary nailing for IT fractures. The primary outcome was revision rate, while secondary outcomes included rates of infection, dislocation, subsidence, and periprosthetic fracture (PPF). A random-effects model was employed to pool overall and implant-specific complication rates.

resultsSeventeen studies with 1,253 cTHA patients met inclusion criteria. Implant type was specified in 799 cases: primary cementless (47.9%), primary cemented (38.8%), diaphyseal cementless (12.0%), and diaphyseal cemented (1.3%). Overall revision rate was 6.7%, infection rate was 3.3%, dislocation rate was 4.5%, and PPF rate was 5.9%. Subgroup analysis across six studies allowed for comparison between primary cementless (n = 265), primary cemented (n = 220), and diaphyseal cementless (n = 17) implants. Cemented stems had a revision rate of 2.4%, an infection rate of 1.8%, a dislocation rate of 2.4%, a subsidence rate of 3.8%, and a PPF rate of 3.2%, compared to cementless (10.1%, 2.8%, 3.3%, 8.1%, 7.7%) and diaphyseal cementless (7.0%, 8.9%, 18.3%, 7.0%, 7.0%) stems.

conclusioncTHA is an effective salvage option for failed IT fracture fixation but carries notable postoperative risks compared to primary THA. Optimal outcomes require careful femoral component selection tailored to patient-specific factors.

Indexed as

Arthroplasty, Replacement, HipFracture Fixation, IntramedullaryPostoperative ComplicationsReoperationHumansPeriprosthetic FracturesProximal Femoral FracturesCephalomedullary nailingComplicationsConversion total hip arthroplastyIntertrochanteric fracturePeriprosthetic fractureRevision

Identifiers

PMID41712004
PMCPMC12920368

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.