Evidence map›Paper›PMID 41711966›Full record

ArticleEuropean journal of nutrition2026

Macronutrient intakes and associations with psoriasis severity: a cross-sectional analysis of the asking people with psoriasis about lifestyle and eating (APPLE) study.

Sylvia Zanesco, Thiviyani Maruthappu, Christopher E M Griffiths, Ruotong Zhang, Kathryn V Dalrymple, Rachel Gibson, Wendy L Hall

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Article in European journal of nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Sylvia ZanescoDepartment of Nutritional Sciences, King's College London, London, UK. sylvia.1.zanesco@kcl.ac.uk.ORCID https://orcid.org/0000-0001-8898-8540
Thiviyani MaruthappuDepartment of Nutritional Sciences, King's College London, London, UK.
Christopher E M GriffithsDepartment of Dermatology, King's College Hospital, King's College London, London, UK.
Ruotong ZhangDepartment of Nutritional Sciences, King's College London, London, UK.ORCID http://orcid.org/0009-0006-6375-4901
Kathryn V DalrympleDepartment of Nutritional Sciences, King's College London, London, UK.ORCID http://orcid.org/0000-0003-0958-6725
Rachel GibsonDepartment of Nutritional Sciences, King's College London, London, UK.ORCID http://orcid.org/0000-0002-5823-6468
Wendy L HallDepartment of Nutritional Sciences, King's College London, London, UK.ORCID http://orcid.org/0000-0003-1634-6930

Funding

Psoriasis Association Worktribe ref 1121143
6 · The paper itself

Abstract

purposeNutrition in psoriasis management is an area of active research interest, but estimates of macronutrient intakes are lacking. The present study aimed to assess macronutrient intakes of people living with psoriasis in the UK and explore the relationship between their dietary sources and psoriasis severity.

methodsThis was an online cross-sectional study collecting diet and psoriasis severity information from adults with psoriasis. Responses to a Food Frequency Questionnaire and the self-assessed Simplified Psoriasis Index were used to determine nutrient intakes and psoriasis severity.

resultsRelative to Dietary Reference Values, participants with psoriasis (n = 257) reported an overconsumption of % energy from free sugars (median 11.2%, IQR 2.6–37.6) and an underconsumption of fibre (20.2 g/day, IQR 5.9–44.0). Compared to participants in the lowest quartile of intake, those in the highest quartile of intake for % free sugars from beverages were more likely to report high psoriasis severity (adjusted Odds Ratio (OR) 3.85, 95% CI 1.507–9.831, P trend = 0.04), although Body Mass Index (BMI) attenuated this relationship. When fully adjusted, including BMI, elevated intakes of % protein from total meat was associated with increased odds of reporting high psoriasis severity (OR 2.47, CI 0.984–6.196), whilst % protein intakes from plant-based sources (OR 0.36, 0.140–0.915) was inversely associated with reporting high disease severity; P trends ≤ 0.05.

conclusionPrioritising plant-based foods may be beneficial to people living with psoriasis, but this hypothesis needs confirmation from randomised controlled trials.

Indexed as

DietLife StyleNutrientsPsoriasisAdultAgedBody Mass IndexCross-Sectional StudiesDietary FiberDietary ProteinsEnergy IntakeFemaleHumansMaleMiddle AgedSeverity of Illness IndexDietary FiberDietary ProteinsDietFood groupsMacronutrientsNutritionPsoriasisSkin

Identifiers

PMID41711966
PMCPMC12920720

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.