Evidence map›Paper›PMID 41711942›Full record

ArticleArchives of virology2026

Antibody-free detection of influenza viruses on a microarray to study their receptor specificity.

N V Shilova, D R Yermolaeva, A Yu Nokel, A A Chinarev, G V Pazynina, M A Sablina, E A Gordeeva, A B Komissarov, N V Bovin

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

N V ShilovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences, Moscow, Russia. pumatnv@gmail.com.ORCID http://orcid.org/0000-0001-6003-071X
D R YermolaevaLomonosov Moscow State University, Moscow, Russia.
A Yu NokelSemiotik LLC, Moscow, Russia.ORCID http://orcid.org/0000-0003-2903-2279
A A ChinarevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences, Moscow, Russia.ORCID http://orcid.org/0000-0001-6088-9751
G V PazyninaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences, Moscow, Russia.ORCID http://orcid.org/0000-0002-0980-1248
M A SablinaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences, Moscow, Russia.
E A GordeevaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences, Moscow, Russia.
A B KomissarovSmorodintsev Research Institute of Influenza, St. Petersburg, Russia.ORCID http://orcid.org/0000-0003-1733-1255
N V BovinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences, Moscow, Russia.ORCID http://orcid.org/0000-0001-8669-4477

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A convenient tool for identifying glycan receptors of new influenza virus strains is the PGA (printed glycan array), which contains up to a hundred sialoglycans. However, antigen diversity and drift complicate the detection of the virus bound to PGA by antibodies, since, generally speaking, new strain is needed for a new antibody. In this work, the bound virus was visualized on PGA using labeled sialopolymers, namely Neu5Acα2-3Galβ1-4GlcNAcβ-PAA-biotin (for avian viruses) or Neu5Acα2-6Galβ1-4GlcNAcβ-PAA-biotin (for human viruses), where PAA is soluble polyacrylamide. Detection of strains H6N1(Sarma/51c/2006), H7N1(FPV/Rostock/2007) and B19 (Moscow/19/2013) was routinely performed at a level of 16 hemagglutination units.

Indexed as

Influenza A virusMicroarray AnalysisOrthomyxoviridaeReceptors, VirusAnimalsHumansPolysaccharidesPolysaccharidesReceptors, Virus

Identifiers

PMID41711942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.