Evidence map›Paper›PMID 41711877›Full record

ArticleAbdominal radiology (New York)2026

A predictive model combining conventional and contrast-enhanced ultrasound for predicting complete microwave ablation of uterine fibroids: a multi-centre study.

Yuqing Huang, Yahui Ma, Yufeng Wang, Bin Wang, Ya Sun, Nan Zhou, Xuedi Han, Ruyue Tian, Xin Zhang, Yankun Zhao and 4 more

Abstract readMulticenter Study
In one paragraph

Article in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Yuqing HuangDepartment of Ultrasound, Aerospace Center Hospital, Beijing, China.
Yahui MaDepartment of Ultrasound, Aerospace Center Hospital, Beijing, China.
Yufeng WangDepartment of Ultrasound, Aerospace Center Hospital, Beijing, China.
Bin WangDepartment of Intervention Vascular, Aerospace Center Hospital, Beijing, China.
Ya SunDepartment of Ultrasound, Aerospace Center Hospital, Beijing, China.
Nan ZhouDepartment of Ultrasound, Aerospace Center Hospital, Beijing, China.
Xuedi HanDepartment of Ultrasound, Aerospace Center Hospital, Beijing, China.
Ruyue TianDepartment of Ultrasound, Aerospace Center Hospital, Beijing, China.
Xin ZhangDepartment of Ultrasound, Emergency General Hospital, Beijing, China.
Yankun ZhaoJiuyuan District Hospital of Integrated Chinese and Western Medicine, Baotou, China.
Xiaohong SunDepartment of Ultrasound, Yixian Hospital, Baoding, China.
Hao YuDepartment of Intervention Vascular, Aerospace Center Hospital, Beijing, China.
Yandong DengDepartment of Ultrasound, First Affiliated Hospital of Hebei Medical University, Shijiazhuang, China. dyd1977@126.com.
Lei LiangDepartment of Ultrasound, Aerospace Center Hospital, Beijing, China. lianglei_csk@126.com.

Funding

National Natural Science Foundation of China 62371010Sponsored by Science Foundation of AMHT 2024YK07
6 · The paper itself

Abstract

objectiveTo develop a pre-percutaneous microwave ablation (PMWA) model combining conventional ultrasound (CUS) and contrast-enhanced ultrasound (CEUS) for predicting non-perfused volume ratio (NPVR) ≥ 80% in patients with uterine fibroids.

methodsThis multicentre, retrospective study enrolled 276 patients with pathologically confirmed uterine fibroids (training/validation = 140/136). CUS features (maximum diameter, pre-operative volume, location, echo), CEUS parameters (maximum intensity: IMAX), and ablation parameters (energy, time, energy per unit volume [EPV], and time per unit volume [TPV]) were analysed. Multivariate logistic regression identified predictors, and model performance was assessed using the area under the receiver operating characteristic curve (AUC) and clinical decision curve analysis.

resultsMultivariate analysis identified four independent predictors: maximum diameter (odds ratio [OR] = 0.47, p < 0.001), IMAX (OR = 0.34, p = 0.013), energy (OR = 1.01, p = 0.002), and TPV (OR = 0.69, p < 0.001). The prediction model performed well in both the training (AUC = 0.79, 95% confidence interval [CI] = 0.71-0.87) and validation (AUC = 0.70, 95%CI = 0.61-0.79) datasets. P values for the Hosmer-Lemeshow test were 0.263 and 0.980, respectively, and the Brier Score was 0.184.

conclusionThis study established a prediction model based on CUS features, CEUS perfusion parameters, and ablation parameters to evaluate the efficacy of PMWA for uterine fibroids; NPVR ≥ 80% can be predicted using the nomogram. This model enables accurate prediction of the efficacy of PMWA for uterine fibroids, providing profound guidance for pre-operative assessment and intraoperative management in clinical practice and facilitating personalised, precision treatment.

Indexed as

Image EnhancementLeiomyomaMicrowavesUterine NeoplasmsAdultContrast MediaFemaleHumansMiddle AgedPredictive Value of TestsRetrospective StudiesUltrasonographyContrast MediaContrast-enhanced ultrasoundConventional ultrasoundPercutaneous microwave ablationPredictive modelUterine fibroids

Identifiers

PMID41711877
PMCPMC13388352

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.