Evidence map›Paper›PMID 41711824›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026

Trends of clinical vertebral and hip fractures following local government involvement in fracture prevention from 2015 to 2021 in Kure, Japan.

Toshiyuki Mizuno, Manabu Tsukamoto, Hidefumi Teramoto, Takahiko Hamasaki, Taizan Shirakawa, Tsuyoshi Nakagawa, Takuma Yamasaki, Junya Tsukisaka, Nobuo Adachi, Saeko Fujiwara and 1 more

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Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Toshiyuki MizunoSaiseikai Kure Hospital, Kure, Japan.ORCID http://orcid.org/0009-0008-3969-0068
Manabu TsukamotoUniversity of Occupational and Environmental Health, Kitakyushu, Japan. m-tsuka@med.uoeh-u.ac.jp.ORCID http://orcid.org/0000-0003-4577-5072
Hidefumi TeramotoRegional Health Care Council of Kure City, Regional Comprehensive Medical System Study Subcommittee of Osteoporosis, Kure, Japan.
Takahiko HamasakiRegional Health Care Council of Kure City, Regional Comprehensive Medical System Study Subcommittee of Osteoporosis, Kure, Japan.ORCID http://orcid.org/0009-0000-9562-7487
Taizan ShirakawaRegional Health Care Council of Kure City, Regional Comprehensive Medical System Study Subcommittee of Osteoporosis, Kure, Japan.
Tsuyoshi NakagawaRegional Health Care Council of Kure City, Regional Comprehensive Medical System Study Subcommittee of Osteoporosis, Kure, Japan.
Takuma YamasakiRegional Health Care Council of Kure City, Regional Comprehensive Medical System Study Subcommittee of Osteoporosis, Kure, Japan.
Junya TsukisakaHiroshima University, Hiroshima, Japan.ORCID http://orcid.org/0009-0008-3405-5292
Nobuo AdachiHiroshima University, Hiroshima, Japan.ORCID http://orcid.org/0000-0002-5570-3729
Saeko FujiwaraYasuda Women's University, Hiroshima, Japan.ORCID http://orcid.org/0000-0002-0114-5266
Nobukazu OkimotoRegional Health Care Council of Kure City, Regional Comprehensive Medical System Study Subcommittee of Osteoporosis, Kure, Japan.ORCID http://orcid.org/0000-0001-5323-0350

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Community-wide Fracture Liaison Services and educational outreach to local physicians on osteoporosis can effectively reduce the fragility fracture burden at the population level in a super-aged society. PURPOSE: Effective prevention of osteoporosis and fractures requires not only implementing a Fracture Liaison Service (FLS) but also enhancing osteoporosis awareness among local physicians, residents, and the municipality. We examined the impact of multidisciplinary, municipality-supported FLS and osteoporosis awareness activities on the incidence of clinical vertebral and hip fractures in a rapidly ageing urban Japanese population.

methodsWe conducted a population-based pre-post observational study of residents aged ≥ 65 years in Kure, Japan, following the introduction of community-wide FLS and osteoporosis awareness activities. Residents were enrolled in the National Health Insurance or Senior Elderly Care System between 2015 and 2021. Fracture events were identified using insurance claims data and ICD/treatment codes.

resultsOverall, the incidence of clinical vertebral fractures tended to increase until 2017 and then tended to decrease thereafter; the incidence of hip fractures tended to decrease after 2017 in females but not in males. Compared with the incidence in 2017, the age-sex-adjusted incidence ratio was 0.76 (95% CI 0.70-0.83) for clinical vertebral fractures and 0.87 (95% CI 0.78-0.96) for hip fractures in 2015. In 2021, the incidence ratio was 0.89 (95% CI 0.82-0.96) for clinical vertebral fractures and 0.85 (95% CI 0.76-0.94) for hip fractures. During this period, an increase in the number of prescriptions and changes in the prescribing patterns were observed.

conclusionsSignificant reductions in the incidence of both clinical vertebral and hip fractures among women were demonstrated after the launch of a comprehensive fracture prevention project supported by the local government.

Indexed as

Ageing societyFracture Liaison ServiceIncidenceMultidisciplinary collaborationPopulation-based studyPublic health policy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.