ArticlePsycho-oncology2026
Specific Depressive Symptoms and Primary Tumor Location as Potential Predictors of Smoking Maintenance After Head and Neck Cancer Treatment.
Article in Psycho-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundDespite the known benefits of smoking cessation for head and neck cancer (HNC) patients, a significant proportion continue to use tobacco after treatment. Although the causes of this phenomenon are multifactorial, the underlying psychological mechanisms are still poorly understood.
aimInvestigate the influence of sociodemographic, clinicopathological, and psychological factors on smoking cessation after treatment of HNC.
methodsThis study included 71 smoking HNC patients who had completed cancer treatment for at least 12 months. Clinicopathological characteristics and anxiety and depression symptoms extracted the Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) were evaluated in the pre-treatment period. Data on smoking history was assessed through a semi-structured interview.
resultsA proportion of patients with HNC patients (39.4%) continued to smoke immediately after completing cancer treatment, with this proportion rising to 43.7% after 12 months of treatment. Logistic regression analyses showed that the occurrence of the primary tumor in the oral cavity (β = 6.891, P = 0.008) and the psychological symptom of sadness measured by the BDI (β = 5.279, P = 0.023) were predictive of smoking maintenance 12 months after the end of cancer treatment. Feeling like a failure before cancer treatment was the only predictor variable for smoking maintenance immediately after and 12 months after the end of treatment (β = 13.455, p < 0.001; β = 4.537, P = 0.043; respectively).
conclusionThis study presents exploratory insights that identifies pre-treatment specific depressive symptoms and primary tumor location as promising predictive factors for continued tobacco use in patients treated for head and neck cancer.
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