Evidence map›Paper›PMID 41711574›Full record

ArticleAntimicrobial agents and chemotherapy2026

Aminoglycosides enhance meropenem/vaborbactam activity against KPC-producing

Nidhi Singh, Christin M L Jogan, Yanan Zang, Xindi Shan, Yinzhi Lang, Arunkumar Karunanidhi, Jackson V Watkins, Brooke N Curry, Pranita D Tamma, Sophie H Nozick and 4 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biofilm-Mediated Antimicrobial Resistance in PediatricAntibiotics (Basel, Switzerland) · 2026
    Review
  2. Complete genome sequences of KPC-producingMicrobiology resource announcements · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nidhi SinghDepartment of Pharmacy Practice, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, Illinois, USA.
Christin M L JoganDepartment of Pharmacy Practice, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, Illinois, USA.
Yanan ZangDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Orlando, Florida, USA.
Xindi ShanDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Orlando, Florida, USA.
Yinzhi LangDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Orlando, Florida, USA.
Arunkumar KarunanidhiDepartment of Pharmacy Practice, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, Illinois, USA.
Jackson V WatkinsDepartment of Pharmacy Practice, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, Illinois, USA.
Brooke N CurryDepartment of Pharmacy Practice, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, Illinois, USA.
Pranita D TammaDepartment of Pediatrics, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-4143-6324
Sophie H NozickDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Egon A OzerDivision of Infectious Diseases, Department of Medicine, Northwestern University Medical School, Chicago, Illinois, USA.
Alan R HauserDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-4596-7939
Jürgen B BulittaDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Orlando, Florida, USA.
Zackery P BulmanDepartment of Pharmacy Practice, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, Illinois, USA.ORCID 0000-0002-5396-911X

Funding

Precise Combination Strategies Targeting Carbapenem-Resistant Klebsiella pneumoniaeR01AI173064 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Zackery P. Bulman · 2023 to 2026
$3.0M
National Institute of Allergy and Infectious Diseases of the National Institutes of Health R01AI173064National Institute of Allergy and Infectious Diseases of the National Institutes of Health R21AI182709National Institute of Allergy and Infectious Diseases of the National Institutes of Health U19AI135964NIAID NIH HHS R01 AI173064
6 · The paper itself

Abstract

Meropenem/vaborbactam is a preferred treatment option for KPC-producing

Indexed as

AminoglycosidesAnti-Bacterial AgentsBoronic AcidsKlebsiella pneumoniaeMeropenembeta-LactamasesDrug CombinationsHeterocyclic Compounds, 1-RingHumansKlebsiella InfectionsMicrobial Sensitivity TestsAminoglycosidesAnti-Bacterial Agentsbeta-LactamasesBoronic AcidsDrug CombinationsHeterocyclic Compounds, 1-RingMeropenemmeropenem and vaborbactamvaborbactamcombinationsCREhollow fiber infection modelmeropenem/vaborbactammutation frequencypharmacokinetics/pharmacodynamics

Identifiers

PMID41711574
PMCPMC13041348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.