Evidence map›Paper›PMID 41711438›Full record

ArticleInfection and immunity2026

The

Edward J A Schuler, Dhara T Patel, Aidan D Moylan, Daniel P Miller, Richard T Marconi

Abstract read
In one paragraph

Article in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Edward J A SchulerDepartment of Microbiology and Immunology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.ORCID 0000-0002-1847-5712
Dhara T PatelDepartment of Microbiology and Immunology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.ORCID 0009-0009-4689-8358
Aidan D MoylanDepartment of Microbiology and Immunology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.
Daniel P MillerDepartment of Microbiology and Immunology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.ORCID 0000-0002-1332-5870
Richard T MarconiDepartment of Microbiology and Immunology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.ORCID 0000-0002-6035-7306

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leptospirosis is a zoonotic disease that affects humans, companion animals, livestock, and wildlife. There are over 60 species that are established pathogens. Leptospires must rapidly adapt to changing environmental conditions as they pass between the environment and vertebrates. Bioinformatic analyses have identified a putative CdaA-type diadenylate cyclase (DAC) in

Indexed as

Bacterial ProteinsLeptospira interrogansPhosphorus-Oxygen LyasesAnimalsDinucleoside PhosphatesGene Expression Regulation, BacterialHumansBacterial Proteinscyclic diadenosine phosphateDinucleoside PhosphatesPhosphorus-Oxygen LyasesCdaAc-di-AMPdiadenylate cyclaseLeptospiraleptospirosisLIC10844osmoregulation

Identifiers

PMID41711438
PMCPMC12974146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.