ArticleMicrobiologyOpen2026
Green and Ecofriendly Mycosynthesis of Nanocomposite Based on Zinc and Magnesium Oxide Nanoparticles Using Endophytic Sarocladium kiliense: Characterization, Anticancer Activity, Antimicrobial and Antibiofilm Activities.
Article in MicrobiologyOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Unveiling the diversity, bioactive metabolites and therapeutic potential of endophytic fungi of the Apocynaceae family: a comprehensive review.Archives of microbiology · 2026Review
- Sustainable synthesis of mono-, bi- and tri-metallic nanoparticles using endophytic fungi: characterization and different applications.RSC advances · 2026Review
- Synergistic antimicrobial and antibiofilm effects of mycosynthesized MnO-MgO bimetallic nanoparticles against drug-resistant pathogens.BMC microbiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Fungal species are increasingly recognized as efficient bio-factories for the biosynthesis of nanoparticles with distinctive functionalities. In this study, zinc oxide-magnesium oxide nanocomposite (ZnO-MgO NCs) were biologically created employing the Sarocladium kiliense PV248633.1 fungal strain. Ultraviolet-visible spectroscopy confirmed nanoparticle formation through characteristic absorption peaks, while Fourier-transform infrared spectroscopy identified functional groups associated with metal-oxygen bonds. Also, the nanoparticle size and surface characteristics Transmission electron microscopy and dynamic light scattering analyzes revealed an average particle size of 35 nm. Biological assessments demonstrate potent antitumor activity (IC₅₀ = 78.1 µg/mL) against MCF-7 breast cancer cells, alongside minimal cytotoxicity against normal WI-38 cells (IC₅₀ = 218.7 µg/mL), indicating selective toxicity. Antibacterial evaluations showed particularly high efficacy against Acinetobacter baumannii and Pseudomonas aeruginosa occasionally surpassing the performance of cefepime. Dose-dependent antimicrobial activity was confirmed through well diffusion and broth microdilution techniques, with minimum inhibitory concentrations highlighting strong bactericidal potential. Biofilm inhibition assays revealed strain-specific responses, with A. baumannii being the most susceptible. Furthermore, the synergistic combination of the biosynthesized nanocomposite with cefepime enhanced antibacterial outcomes against selected isolates, suggesting potential for addressing drug resistance. Overall, the mycogenic ZnO-MgO NCs synthesized from S. kiliense exhibited substantial anticancer, antibacterial, and antibiofilm properties, locating this nanocomposite as a promising candidate for biomedical purposes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.