In one paragraphArticle in American journal of physiology. Renal physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Hiroki YamaguchiDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, United States.ORCID 0000-0003-2409-7401 Jason P SmithDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, United States.ORCID 0000-0002-2688-0988 Omar GuessoumDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, United States.
Drishti DagaDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, United States.
Manako YamaguchiDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, United States.ORCID 0000-0002-2880-9165 Lucas Ferreira de AlmeidaDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, United States.
Daisuke MatsuokaDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, United States.ORCID 0000-0002-2164-0555 Hirofumi WatanabeDivision of Clinical Nephrology and Rheumatology, Kidney Research Center, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Silvia MedranoDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, United States.ORCID 0000-0002-8516-0788 R Ariel GomezDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, United States.ORCID 0000-0002-5124-8255 Maria Luisa S Sequeira-LopezDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, United States.ORCID 0000-0002-4459-7940 Funding
Single-Cell Epigenomics, Transcriptomics, and Bioinformatics CoreP50DK096373 · NIDDK · UNIVERSITY OF VIRGINIA · PI ROBERTO Ariel GOMEZ · 2012 to 2026
$13.8MRenin cell identity and blood pressure homeostasisR01HL148044 · NHLBI · UNIVERSITY OF VIRGINIA · PI SEQUEIRA-LOPEZ, MARIA LUISA SOLEDAD · 2020 to 2023
$2.7MHHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL148044HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) P50DK096373NHLBI NIH HHS R01 HL148044NIDDK NIH HHS P50 DK096373
6 · The paper itselfAbstract
Renin regulates blood pressure and fluid-electrolyte homeostasis via the renin-angiotensin-aldosterone system (RAAS), and renin cells function as renal baroreceptors that couple perfusion pressure to renin output. Krüppel-like factor 2 (Klf2), a canonical flow-responsive transcription factor, repeatedly emerged from our multiomics profiling linked to renin cell identity, but its role in renin cells remained unknown. We generated mice with renin-lineage-specific
Indexed as
Juxtaglomerular ApparatusKruppel-Like Transcription FactorsReninAnimalsBlood PressureForkhead Transcription FactorsMaleMiceMice, KnockoutRenin-Angiotensin SystemForkhead Transcription FactorsFoxd1 protein, mouseKlf2 protein, mouseKruppel-Like Transcription FactorsReninblood pressurereninrenin-angiotensin system
Identifiers
PMID41711369
PMCPMC13382476
What OpenQuestion holds
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