Evidence map›Paper›PMID 41710941›Full record

ArticleFrontiers in cell and developmental biology2026

Platelet-activating factor modulates apoptotic gene expression in developing sea urchin embryos.

Shohom Saha, Aaron Cho, Caroline Smith, William E Roudebush, Renee J Chosed

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shohom SahaDepartment of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, SC, United States.
Aaron ChoDepartment of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, SC, United States.
Caroline SmithDepartment of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, SC, United States.
William E RoudebushDepartment of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, SC, United States.
Renee J ChosedDepartment of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, SC, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Examining gene expression patterns during early embryonic development is essential for understanding genetic disorders and fertility. The accessibility, cost-effectiveness, and reproducibility of sea urchin embryos have offered an effective model for studying how gene expression is regulated in early embryogenesis under the influence of specific growth factors. However, regulation of apoptotic gene expression by growth factors, such as Platelet-Activating Factor (PAF), during early embryogenesis remains unexamined. This study investigated the role of PAF during the first 4 hours post-fertilization in sea urchin (

Indexed as

apoptosiscaspaseplatelet-activating factorsea urchinssignaling / signaling pathways

Identifiers

PMID41710941
PMCPMC12909567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.