ArticleFrontiers in veterinary science2026
Chinese yam polysaccharide promotes jejunal development, antioxidant defense, and mucosal immunity in weaned rats.
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- A Novel Hydrophilic Colloidal Polysaccharide fromFoods (Basel, Switzerland) · 2026Article
- Clinical study and the diagnosis of lumpy skin disease in cattle using genomic, immunological, and pathological indicators.Frontiers in veterinary science · 2026Article
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9 authors.
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Abstract
Introduction: Chinese yam polysaccharide (CYP), a heteropolysaccharide composed of mannose, xylose, arabinose, glucose, and galactose, has been reported to exhibit immunomodulatory and antioxidant properties. However, its role in regulating intestinal development and mucosal barrier function remains incompletely understood. This study investigated the effects of dietary CYP supplementation on antioxidant status, jejunal morphology, digestive function, and mucosal immunity in weaned rats. Methods: Thirty specific-pathogen-free male Sprague-Dawley rats (initial body weight: 50.16 ± 0.50 g) were randomly assigned to three dietary groups (n = 10 per group) for a 28-day feeding trial: a control group fed a basal diet and two treatment groups fed the basal diet supplemented with 0.1% or 0.5% CYP. At the end of the experiment, blood and jejunal tissues were collected for biochemical, histomorphological, and molecular analyses. Results: Compared with the control group, supplementation with 0.5% CYP significantly reduced plasma malondialdehyde (MDA) concentrations ( Discussion: Collectively, these findings demonstrate that dietary CYP enhances systemic antioxidant defense, promotes jejunal structural development, and strengthens intestinal mucosal barrier function in weaned rats.
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