Evidence map›Paper›PMID 41710863›Full record

ArticleCureus2026

Severe Manifestation of Hyperparathyroidism With Sagliker Syndrome: A Case Report.

Mario Manuel Morantes Salazar, Jenny Carolina Salazar Florez, Nathalia Jacome-Pérez, William Darío Arenas Borda, Camilo Andrés Lara Rodríguez

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Sagliker Syndrome: A Diagnostic Challenge.Contemporary clinical dentistry
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mario Manuel Morantes SalazarGeneral Medicine, Industrial University of Santander, Bucaramanga, COL.
Jenny Carolina Salazar FlorezRadiology, University of Santander, Bucaramanga, COL.
Nathalia Jacome-PérezRadiology, University of Santander, Bucaramanga, COL.
William Darío Arenas BordaNeuroradiology, Instituto de Diagnóstico Médico, Bucaramanga, COL.
Camilo Andrés Lara RodríguezNeuroradiology, Instituto de Diagnóstico Médico, Bucaramanga, COL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sagliker syndrome represents a rare and severe manifestation of secondary renal osteodystrophy in patients with end-stage chronic kidney disease. We present the case of a 26-year-old woman on peritoneal dialysis with a one-year history of progressive craniofacial deformity involving both the maxilla and mandible. Laboratory tests demonstrated markedly elevated parathyroid hormone levels (1,936 pg/mL). Cranial CT revealed a diffuse "salt and pepper" pattern, serpiginous lytic trabecular changes, and focal ground-glass areas in the calvarium. Correlation of severe hyperparathyroidism with these characteristic imaging features confirmed Sagliker syndrome. Early recognition is essential to prevent irreversible deformities and long-term morbidity. The patient was managed through a multidisciplinary approach, including medical optimization of secondary hyperparathyroidism, followed by total parathyroidectomy due to persistent biochemical abnormalities and progressive craniofacial deformity.

Indexed as

chronic kidney disease-mineral and bone disorderchronic renal insufficiencyhyperparathyroidismrenal insufficiencysagliker syndrome

Identifiers

PMID41710863
PMCPMC12909286

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.