ArticleCureus2026
Genome-Wide Association Study (GWAS)-Derived Type 2 Diabetes Risk Variants in Gestational Diabetes Mellitus: Evidence From North India.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionGestational diabetes mellitus (GDM) is hyperglycaemia first identified during pregnancy. Because GDM and type 2 diabetes mellitus (T2DM) share insulin resistance and β-cell dysfunction, T2DM variants may also influence the risk of GDM. This study examined the association of three genome-wide association study (GWAS)-identified T2DM variants, AP3S2 rs2028299 (C>A), ST6GAL1 rs16861329 (C>T), and VPS26A rs1802295 (C>T), with GDM susceptibility in pregnant women from North India.
methodsThis observational case-control study was conducted at the tertiary care antenatal clinic of a medical university in Uttar Pradesh, India, and included 69 women with GDM and 69 age- and BMI-matched non-GDM controls. GDM was diagnosed using a one-step 75 g oral glucose tolerance test (OGTT) according to the Diabetes in Pregnancy Study Group India (DIPSI) criteria (DIPSI ≥140 mg/dL). Genotyping of the three variants was performed using polymerase chain reaction followed by Sanger sequencing.
resultsWomen with GDM had higher triglyceride (p=0.037) and VLDL (p=0.006) levels than controls. A family history of T2DM was significantly associated with GDM (p=0.024). The
conclusionIn this North Indian case-control study, rs2028299 (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.