Evidence map›Paper›PMID 41710775›Full record

ArticleTherapeutic advances in gastroenterology2026

Comparative risk of

Jiahui Huang, Min Zhang, Jun Deng, Jiayin Yao, Xiang Peng, Qi Zhang, Min Zhi, Tao Liu

Abstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiahui HuangDepartment of Clinical Laboratory, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Min ZhangDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jun DengDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jiayin YaoDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xiang PengDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Qi ZhangDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0009-0004-1979-5891
Min ZhiDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, No. 26 Yuancun Erheng Road, Tianhe District, Guangzhou, Guangdong 510655, China.ORCID https://orcid.org/0000-0003-4475-4704
Tao LiuDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, No. 26 Yuancun Erheng Road, Tianhe District, Guangzhou, Guangdong 510655, China.ORCID https://orcid.org/0000-0003-3174-1226

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antitumor necrosis factor (anti-TNF) agents are associated with an increased risk of Objectives: To compare the incidence densities (IDs) and risks of CDI and Design: Single-center retrospective cohort study. Methods: In a retrospective cohort study, we included 627 CD patients with a negative baseline Results: The cohort included 277 patients (381 person-years, PY) treated with UST and 350 patients (454 PY) treated with anti-TNF agents. CDI developed in 4 of 277 UST-treated participants (1.05/100 PY) and 9 of 350 anti-TNF-treated participants (1.98/100 PY), corresponding to an IDR of 0. Conclusion: In this real-world cohort, treatment with UST was not associated with a significantly higher risk of CDI or

Indexed as

anti-TNFClostridioides difficileCrohn’s diseaseinfectionustekinumab

Identifiers

PMID41710775
PMCPMC12909749

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.