Evidence map›Paper›PMID 41710694›Full record

ArticleJournal of oral microbiology2026

A comparative study on arginine metabolism by oral streptococci revealed both divergence and heterogeneity in dependence on arginine and significance of ornithine and citrulline.

Lin Zeng

Abstract read
In one paragraph

Article in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Lin ZengDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, USA.ORCID https://orcid.org/0000-0002-9269-2707

Funding

GENE REGULATION AND PHYSIOLOGY OF STREPTOCOCCUS MUTANSR01DE012236 · NIDCR · UNIVERSITY OF ROCHESTER · PI Lin Zeng · 1997 to 2026
$8.5M
NIDCR NIH HHS R01 DE012236
6 · The paper itself

Abstract

Background: Current understanding in arginine metabolism by streptococci is limited in species and strains. Objectives: We compared the ability of several abundant oral streptococci to synthesize and assimilate arginine. Design: Multiple species of oral streptococci and their genetic mutants were characterized for growth using synthetic media with specified amounts of arginine and related amino acids. Expression of relevant genes was quantified by RT-qPCR. Results: An intact arginine deiminase system (ADS) was required for Conclusions: Our study suggested that arginine is an essential nutrient for most oral streptococci, excluding

Indexed as

Argininearginine deiminase systemcitrullinecommensal streptococciornithinestreptococcus mutans

Identifiers

PMID41710694
PMCPMC12912212

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.