Evidence map›Paper›PMID 41710615›Full record

ArticleSaudi journal of anaesthesia

Regional anesthesia in breast surgery: An Italian expert consensus - Part 1: Methodology and Delphi strategy.

Domenico P Santonastaso, Alessandro De Cassai, Eros Pilia, Francesco Coppolino, Gabriele Melegari, Federico Piccioni, Fabrizio Fattorini, Andrea Tognù, Giuseppe Sepolvere, Paolo Scimia and 23 more

Abstract read
In one paragraph

Article in Saudi journal of anaesthesia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Domenico P SantonastasoDepartment of Anesthesia and Intensive Care Unit, AUSL Romagna, M. Bufalini Hospital, Cesena, Italy.
Alessandro De CassaiInstitute of Anesthesia and Intensive Care, Padua University Hospital, Padua, Italy.
Eros PiliaDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Francesco CoppolinoDepartment of Women, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.
Gabriele MelegariDepartment of Anesthesia and Intesive Care, Azienda Ospedaliero Universitaria Policlinico di Modena, Modena, Italy.
Federico PiccioniDepartment of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy.
Fabrizio FattoriniDepartment of Anesthesia, San Sebastiano Hospital, Frascati, Rome, Italy.
Andrea TognùDepartment of Anesthesia, Intensive Care and Pain Medicine Unit, ASST Gaetano Pini-CTO, Milano, Italy.
Giuseppe SepolvereDepartment of Anesthesia and Cardiac Surgery Intensive Care Unit, Casa Di Cura San Michele, Maddaloni, Caserta, Italy.
Paolo ScimiaDepartment of Anesthesia and Intensive Care Unit, Giuseppe Mazzini Hospital, Teramo, Italy.
Annalisa CurcioBreast Surgery Unit, Morgagni-Pierantoni Hospital, Forlì, Italy.
Claude T BagaphouSection of Anesthesia, Intensive Care and Pain Medicine, Ospedale di Castello, Città di Castello, Perugia, Italy.
Antonio CovielloDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Naples, Italy.
Alessandra MorelliDepartment of Anesthesia and Intensive Care Unit, AUSL Romagna, M. Bufalini Hospital, Cesena, Italy.
Diego MarandolaDepartment of Anesthesia and Intensive Care Unit, AUSL Romagna, M. Bufalini Hospital, Cesena, Italy.
Dario PietrantozziDepartment of Anesthesia and Intensive Care Unit, AUSL Romagna, M. Bufalini Hospital, Cesena, Italy.
Mario TedescoDepartment of Anesthesia and Intensive Care Unit and Pain Therapy, Mater Dei Hospital, Bari, Italy.
Alessandra GentiliDepartment of Anesthesia and Intensive Care Unit, Principe di Piemonte Hospital, Senigallia, Italy.
Marco RispoliDepartment of Anesthesia and Intensive Care, AO dei Colli - Monaldi Hospital, Naples, Italy.
Giuseppe LubranoBuonconsiglio Fatebenefratelli Hospital, Naples, Italy.
Dario M MattiacciDepartment of Anesthesia and Intensive Care, AO dei Colli - Monaldi Hospital, Naples, Italy.
Moana R NespoliDepartment of Anesthesia and Intensive Care, AO dei Colli - Monaldi Hospital, Naples, Italy.
Cristiano D'ErricoNew Coastal Hospital - Sorrento, Naples, Italy.
Fabio CostaDepartment of Anesthesia and Intensive Care Unit, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Federico BizzarriAUSL-IRCCS-Reggio Emilia, Rome, Italy.
Giorgio RanieriDepartment of Emergency and Internal Medicine, UOC Anesthesia and Operating Theaters, Isola Tiberina Hospital - Gemelli Isola, Rome, Italy.
Nicola RoccoDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Tommaso TonettiDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Secondo FolliDepartment of Breast Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
Annabella de ChiaraDepartment of Anesthesia and Intensive Care Unit, AUSL Romagna, M. Bufalini Hospital, Cesena, Italy.
Maria C PaceDepartment of Women, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.
Pierfrancesco FuscoDepartment of Anesthesia and Intensive Care, Santi Filippo and Nicola Hospital, Avezzano, L'Aquila, Italy.
Vanni AgnolettiDepartment of Anesthesia and Intensive Care Unit, AUSL Romagna, M. Bufalini Hospital, Cesena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Despite being considered routine, breast surgery is associated with a high incidence of acute and chronic postoperative pain, which can significantly impact recovery and quality of life. Regional anesthesia techniques have become increasingly relevant within multimodal analgesic strategies, yet clinical practice remains heterogeneous and lacks clear guidance. To address this, we aimed to develop a multidisciplinary, evidence-based consensus on the role of regional anesthesia in breast surgery. Methods: An expert panel was appointed by the Italian Chapter of the European Society of Regional Anaesthesia, including anesthesiologists and breast surgeons (in partnership with the Italian National Association of Breast Surgeons). A four-round Delphi method was applied to refine an initial set of 24 PICO-formulated questions. Each question was evaluated for relevance and clarity using a 9-point Likert scale (1 = not relevant/clear, 9 = extremely relevant/clear). Finalized questions underwent systematic review or network meta-analysis depending on data availability. Results: Eleven clinically relevant and clearly formulated PICO questions were identified after four Delphi rounds. These questions encompass acute and chronic pain control, block safety in anticoagulated patients, awake surgery, and the comparative efficacy of single-shot versus continuous blocks, among others. Each question will guide a systematic review and support the development of graded consensus statements. Conclusion: This consensus project establishes a transparent, multidisciplinary framework for guiding the use of regional anesthesia in breast surgery. The ultimate objective is to formulate a set of consensus statements, graded according to evidence strength, which will serve as a foundation for future guidelines and standardized clinical decision-making.

Indexed as

Breast surgeryconsensusdelphi consensusregional anesthesia

Identifiers

PMID41710615
PMCPMC12912528

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.