Evidence map›Paper›PMID 41710522›Full record

ArticleFrontiers in toxicology2026

Foreign body reaction: towards a macrophage-centered adverse outcome pathway for fibrotic encapsulation.

Tom Meseberg, Susanne Kurz, Juliane Spohn

Abstract read
In one paragraph

Article in Frontiers in toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tom MesebergBio- and Nanotechnology Department, Fraunhofer Institute for Ceramic Technologies and Systems (FHG), Dresden, Germany.
Susanne KurzBio- and Nanotechnology Department, Fraunhofer Institute for Ceramic Technologies and Systems (FHG), Dresden, Germany.
Juliane SpohnBio- and Nanotechnology Department, Fraunhofer Institute for Ceramic Technologies and Systems (FHG), Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The foreign body reaction (FBR), characterized by chronic inflammation and fibrotic capsule formation around implanted medical devices, remains a major cause in device-related complications. Current preclinical risk assessment relies on

Indexed as

adverse outcome pathway (AOP)biomaterialsforeign body reactionimmunotoxicologyISO 10993macropagemedical devices

Identifiers

PMID41710522
PMCPMC12912714

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.