Evidence map›Paper›PMID 41710492›Full record

ArticleRSC advances2026

Development of bioactive SF/HAp/ZnO scaffolds incorporating succinic acid with potential bone regeneration capabilities.

Sadia Habib, Aysha Arshad, Hafsah Akhtar, Fahad Hussain Alhamoudi, Gülderen Karakuş, Gültekin Gökce, Aqif Anwar Chaudhry, Hamad Khalid, Ather Farooq Khan

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sadia HabibInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad, Lahore Campus Defence Road, off Raiwind Road Lahore Pakistan ather.khan@aasu.edu.kw.ORCID https://orcid.org/0009-0006-6462-7007
Aysha ArshadInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad, Lahore Campus Defence Road, off Raiwind Road Lahore Pakistan ather.khan@aasu.edu.kw.
Hafsah AkhtarInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad, Lahore Campus Defence Road, off Raiwind Road Lahore Pakistan ather.khan@aasu.edu.kw.ORCID https://orcid.org/0000-0002-4928-6957
Fahad Hussain AlhamoudiDental Technology Department Applied Medical Science, King Khalid University Abha 62529 Kingdom of Saudi Arabia.ORCID https://orcid.org/0000-0002-8391-1787
Gülderen KarakuşDepartment of Pharmaceutical Basic Sciences, Sivas Cumhuriyet University Faculty of Pharmacy 58140 Sivas Türkiye.
Gültekin GökceDepartment of Analytical Chemistry, Sivas Cumhuriyet University Faculty of Pharmacy 58140 Sivas Türkiye.
Aqif Anwar ChaudhryInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad, Lahore Campus Defence Road, off Raiwind Road Lahore Pakistan ather.khan@aasu.edu.kw.
Hamad KhalidInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad, Lahore Campus Defence Road, off Raiwind Road Lahore Pakistan ather.khan@aasu.edu.kw.
Ather Farooq KhanInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University Islamabad, Lahore Campus Defence Road, off Raiwind Road Lahore Pakistan ather.khan@aasu.edu.kw.ORCID https://orcid.org/0000-0002-5178-2482

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The challenges associated with using autografts for repairing bone defects have increased the demand for synthetic bone graft substitutes that can offer both structural support and biological activity. In this research, we developed a composite scaffold made of silk fibroin, hydroxyapatite, and ZnO (SF/HAp/ZnO), incorporating succinic acid (SA) as a functional additive to improve the physicochemical and biological properties of the scaffold. The morphology of the synthesized scaffold was confirmed by FESEM analysis, and a rougher morphology than pure SF was observed in the scaffolds. The study revealed that the scaffold displayed slow degradation (4.84% after 21 days in S4) and high swelling

Identifiers

PMID41710492
PMCPMC12910347

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.