Evidence map›Paper›PMID 41710485›Full record

ArticleTobacco induced diseases2026

The declining but persistent burden of lower respiratory infections from secondhand smoke in children aged under 14 years: Global trends 1990-2021 and forecasts to 2035, based on a secondary dataset analysis of Global Burden of Disease (GBD) 2021.

Fan Yang, Yiyang Zhu, Changjing Hu, Xuehong Dong, Caiping Liu, Yuxuan Li, Zifei Pan, Yue Yang, Xiaomin Jin, Qian He and 4 more

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Article in Tobacco induced diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

14 authors.

Fan Yang *Department of Pharmacy, Jiangsu Ocean University, Lianyungang, China.
Yiyang Zhu *School of Chinese Medicine, Macau University of Science and Technology, Macau, China.
Changjing HuDepartment of Pharmacy, Jiangsu Ocean University, Lianyungang, China.
Xuehong DongDepartment of Pharmacy, Jiangsu Ocean University, Lianyungang, China.
Caiping LiuDepartment of Pharmacy, Jiangsu Ocean University, Lianyungang, China.
Yuxuan LiDepartment of Pharmacy, Jiangsu Ocean University, Lianyungang, China.
Zifei PanDepartment of Pharmacy, Jiangsu Ocean University, Lianyungang, China.
Yue YangDepartment of Pharmacy, Jiangsu Ocean University, Lianyungang, China.
Xiaomin JinDepartment of Pharmacy, Jiangsu Ocean University, Lianyungang, China.
Qian HeDepartment of Pharmacy, Jiangsu Ocean University, Lianyungang, China.
Qingqing WangDepartment of Pharmacy, Jiangsu Ocean University, Lianyungang, China.
Lan SunJiangsu Food and Pharmaceutical Science College, Huaian, China.
Qingxia LiChia Tai Tianqing Pharmaceutical Group Co., Ltd, Lianyungang, China.
Jinyang ShenDepartment of Pharmacy, Jiangsu Ocean University, Lianyungang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough global smoke-free policies have significantly reduced smoking rates, exposure to secondhand smoke (SHS) in homes and public places remains common. SHS continues to be a significant risk factor for lower respiratory infections (LRIs) in children. However, there is still a lack of systematic assessment of the spatiotemporal trends and future disease burden of LRIs attributable to SHS in children aged under 14 years.

methodsThis study is a secondary analysis of the Global Burden of Disease (GBD) 2021 data. We used joinpoint regression to analyze trends and calculate the average annual percentage change (AAPC) in the burden of LRIs attributable to SHS among children aged under 14 years, globally from 1990 to 2021. Age-standardized rates (ASRs) of mortality and DALYs were quantified at the global, regional, and national levels. Finally, a Bayesian age-period-cohort (BAPC) model was applied to forecast trends up to 2035, providing a basis for formulating targeted intervention strategies.

resultsIn 2021, the number of deaths and disability-adjusted life years (DALYs) among children aged under 14 years worldwide due to LRIs caused by SHS decreased significantly. The ASR declined to 2.25 (95% UI: 0.73-3.86) for mortality and 199.84 (95% UI: 64.82-342.97) for DALYs per 100000 population. The forecast results indicated that by 2035, both the mortality and the DALY rates would continue to decline.

conclusionsAlthough the global burden had declined significantly and was expected to continue decreasing through 2035, SHS remained a significant contributor to LRIs in children.

Indexed as

childrenGBD 2021lower respiratory infectionspredictionsecondhand smoke

Identifiers

PMID41710485
PMCPMC12911320

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