ArticleFrontiers in endocrinology2026
Short-term vs. overnight insemination: which one is better for patients with only one or two oocytes retrieved in IVF cycles?
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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11 authors.
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Abstract
Background: Compared with overnight insemination, it remains uncertain whether short-term insemination can improve outcomes in poor responders, and few studies have used cumulative live birth rate as the primary endpoint. The study aims to compare the effects of short-term insemination and overnight insemination on poor responders with one or two oocytes by evaluating cumulative live births. Methods: A retrospective study was conducted on 2,392 cycles, which were divided into the short-term insemination group (5 h) and the overnight insemination group (17 h) based on gametes' incubation time. Basic characteristics and clinical outcomes were compared and analyzed using propensity score matching. Results: The short-term insemination group got more normal fertilized embryos than the overnight insemination group ( Conclusions: Our analysis suggests that for IVF cycles with a limited oocyte yield (1-2), short-term insemination does not adversely affect the CLBR. Furthermore, it may demonstrate a potential benefit for the subset of patients whose clinical pathway involves the extended culture of all embryos to the blastocyst stage.
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