ArticleJournal of multidisciplinary healthcare2026
Risk Factors Influencing Disease Onset and Surgical Outcomes in Moyamoya Disease.
Article in Journal of multidisciplinary healthcare, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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8 authors.
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Abstract
Objective: The aim of this study is to explore the risk factors associated with the onset and clinical progression of moyamoya disease (MMD), as well as the outcomes of combined revascularization surgery (RS). Methods: A retrospective analysis was performed on the medical records of 226 individuals diagnosed with MMD who underwent combined Results: Hypertension (odds ratio [OR] = 1.816, 95% confidence interval [CI]: 1.031-3.197) and higher preoperative modified Rankin Scale scores (OR = 5.164, 95% CI: 1.145-23.295) were identified as independent risk factors for CIS. Male sex (OR = 4.219, 95% CI: 1.470-12.195) and age ≥ 50 years (OR = 3.979, 95% CI: 1.494-10.598) were independent predictors of postoperative complications following RS. No independent factors were associated with the affected side or bilateral progression of MMD (P > 0.05). Disease severity in patients with CIS was influenced by both Suzuki staging and age. The effective rate of Conclusion: Early intervention is recommended, particularly for male patients and those with modifiable risk factors such as hypertension.
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