Evidence map›Paper›PMID 41710338›Full record

ArticlePatient preference and adherence2026

Perspectives of Healthcare Professionals on the Treatment Landscape of Ocular Redness.

Melissa M Toyos, Katie Forster, Sara Savar, Saskia Aguado, Kyriakos Kiskiras, Ertugrul Akbas, Melinda DiVito, Robert Ryan, Katy Gallop, Kostas Boboridis and 2 more

Abstract read
In one paragraph

Article in Patient preference and adherence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Melissa M ToyosToyos Clinic, Nashville, TN, USA.ORCID 0000-0003-4529-9643
Katie ForsterAcaster Lloyd Consulting Ltd., London, UK.ORCID 0009-0001-6073-1791
Sara SavarAcaster Lloyd Consulting Ltd., London, UK.
Saskia AguadoGlobal Medical Affairs, Bausch & Lomb, Bridgewater, NJ, USA.
Kyriakos KiskirasGlobal Medical Affairs, Bausch & Lomb, Bridgewater, NJ, USA.
Ertugrul AkbasGlobal Medical Affairs, Bausch & Lomb, Bridgewater, NJ, USA.
Melinda DiVitoGlobal Medical Affairs, Bausch & Lomb, Bridgewater, NJ, USA.
Robert RyanGlobal Medical Affairs, Bausch & Lomb, Bridgewater, NJ, USA.
Katy GallopAcaster Lloyd Consulting Ltd., London, UK.ORCID 0000-0002-6826-3865
Kostas BoboridisOphthalmica Eye Institute, Thessaloniki, Greece.ORCID 0000-0002-0471-0371
José Manuel Salgado-BorgesClinsborges, Porto, Portugal.
Jorge L AlioDepartment of Ophthalmology, Miguel Hernandez University; Vissum Miranza Alicante, Alicante, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ocular redness (OR) is a common clinical presentation that can significantly impact patients' health-related quality of life (HRQoL), yet treatment options have historically been limited by side effects and efficacy concerns. Brimonidine tartrate 0.025% represents a newer therapeutic option, but real-world perspectives from healthcare professionals (HCPs) on its clinical utility remain understudied. Methods: A cross-sectional exploratory qualitative interview study was conducted with 18 ophthalmologists purposively recruited from a sponsor-acquired list. Participants had experience prescribing or recommending brimonidine tartrate 0.025% and were interviewed across Spain, Portugal, Poland, the United States, and Greece. Semi-structured interviews explored current treatment landscapes, unmet needs, and experiences with brimonidine tartrate 0.025%. Transcripts were analysed using qualitative content analysis. Results: Participants reported OR as highly prevalent in their practice, with dry eye disease being the most commonly cited underlying cause. HCPs described significant HRQoL impact on patients, including social embarrassment, workplace concerns, and emotional distress. Prior to brimonidine tartrate 0.025%, treatment options were limited, with traditional vasoconstrictors avoided due to rebound redness and tachyphylaxis. All participants reported brimonidine tartrate 0.025% as effective, with rapid onset and good tolerability. Key advantages included lack of rebound redness and suitability for various patient types. Conclusion: This study with brimonidine tartrate 0.025% prescribers found it addresses a significant unmet need in OR management, providing effective relief with improved safety profile compared to traditional options. However, emphasis on proper diagnosis and use remains crucial.

Indexed as

brimonidine tartrateconjunctival hyperaemiahealthcare professionalsocular rednessqualitative researchtreatment satisfaction

Identifiers

PMID41710338
PMCPMC12912081

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.