Evidence map›Paper›PMID 41710137›Full record

ArticleJournal of diabetes research2026

Exploring the Use of Hybrid Closed-Loop Systems in People With Type 1 Diabetes and Their Partners: A Qualitative Evaluation From the NHS England Pilot.

Jennifer Hagan, Tomás P Griffin, Radhika Chauhan, Pratik Choudhary, Thomas S J Crabtree, Dawn Ackroyd, Emma G Wilmot, Parth Narendran, Zosanglura Bawlchhim, Jackie Elliott and 1 more

Abstract read
In one paragraph

Article in Journal of diabetes research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jennifer HaganDiabetes Research Centre, College of Health Sciences, University of Leicester, Leicester, UK, le.ac.uk.ORCID https://orcid.org/0009-0000-7263-8095
Tomás P GriffinDiabetes Research Centre, College of Health Sciences, University of Leicester, Leicester, UK, le.ac.uk.ORCID https://orcid.org/0000-0003-1625-9394
Radhika ChauhanDiabetes Research Centre, College of Health Sciences, University of Leicester, Leicester, UK, le.ac.uk.ORCID https://orcid.org/0000-0002-0539-1886
Pratik ChoudharyDiabetes Research Centre, College of Health Sciences, University of Leicester, Leicester, UK, le.ac.uk.ORCID https://orcid.org/0000-0001-7635-4735
Thomas S J CrabtreeDepartment of Diabetes & Endocrinology, Royal Derby Hospital, University Hospitals of Derby and Burton NHS Trust, Derby, UK, nhs.uk.ORCID https://orcid.org/0000-0001-7886-8262
Dawn AckroydLeicester Diabetes Centre, University Hospitals of Leicester, Leicester, UK, nhs.uk.
Emma G WilmotDepartment of Diabetes & Endocrinology, Royal Derby Hospital, University Hospitals of Derby and Burton NHS Trust, Derby, UK, nhs.uk.ORCID https://orcid.org/0000-0002-8698-6207
Parth NarendranDepartment of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK, birmingham.ac.uk.ORCID https://orcid.org/0000-0002-4583-8793
Zosanglura BawlchhimCEDAR Centre, Department of Diabetes, Royal Surrey NHS Foundation Trust, Guildford, UK.ORCID https://orcid.org/0000-0001-8783-1955
Jackie ElliottDiabetes and Endocrine Centre, Sheffield Teaching Hospitals, Department of Oncology and Metabolism, The University of Sheffield, Sheffield, UK, sheffield.ac.uk.ORCID https://orcid.org/0000-0002-7867-9987
Michelle HadjiconstantinouDiabetes Research Centre, College of Health Sciences, University of Leicester, Leicester, UK, le.ac.uk.ORCID https://orcid.org/0000-0003-2827-0988

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: The NHS England hybrid closed-loop (HCL) insulin pump pilot offered people living with Type 1 diabetes (PWT1Ds) access to HCL therapy. Outcomes demonstrated the glycaemic benefits of HCL. Our study explored the views, experiences and impact of HCL on users and their partners' daily life. Methods: A total of 14 PWT1Ds and 12 partners of PWT1Ds who participated in the NHS HCL pilot took part in semistructured interviews via telephone/video call. Topics explored included the effect of the HCL system on glucose levels, time spent managing diabetes, daily life and challenges with the systems. Interviews were audio-recorded and transcribed. Data was analysed using inductive thematic analysis and then mapped onto an adapted Optimal Health Wheel (OHW) framework encompassing four relevant domains: (i) emotional, (ii) intellectual, (iii) social and (iv) physical. Results: Ten subthemes relating to the impact or experience of using HCL emerged-knowledge and previous experience, time/trial and error, building trust, impact on mental wellbeing, impact on physical health, impact on diabetes management, impact on lifestyle, impact on work, impact on relationships and need for support. PWT1Ds and partners reported multifaceted physiological and psychosocial benefits of using HCL systems. While technical difficulties and initial learning hurdles were acknowledged as barriers to HCL use, facilitators such as previous experience and trial and error helped overcome these issues. Conclusions: PWT1Ds and their partners endorsed the use of HCL systems, despite challenges, due to the impactful benefits to their lives. To ensure future successful implementation of HCL, users should be offered appropriate training and access to support to help build trust. These findings underscore the potential of HCL systems in T1D treatment.

Indexed as

Diabetes Mellitus, Type 1Glycemic ControlHypoglycemic AgentsInsulinInsulin Infusion SystemsAdultBlood GlucoseBlood Glucose Self-MonitoringEnglandFemaleHumansMaleMiddle AgedPilot ProjectsQualitative ResearchBlood GlucoseHypoglycemic AgentsInsulinexperienceshybrid closed-loopqualitativeType 1 diabetes

Identifiers

PMID41710137
PMCPMC12909262

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.