Evidence map›Paper›PMID 41710089›Full record

ArticleEJHaem2026

Effect of Early Administration of Anti-MRSA Drugs for Febrile Neutropenia in Allogeneic Hematopoietic Cell Transplantation.

Anna Akaogi, Junya Kanda, Fumiya Wada, Yasuyuki Arai, Chisaki Mizumoto, Toshio Kitawaki, Kouhei Yamashita, Akifumi Takaori-Kondo

Abstract read
In one paragraph

Article in EJHaem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anna AkaogiDepartment of Hematology Graduate School of Medicine Kyoto University Kyoto Japan.ORCID https://orcid.org/0009-0005-3020-0390
Junya KandaDepartment of Hematology Graduate School of Medicine Kyoto University Kyoto Japan.
Fumiya WadaDepartment of Hematology Graduate School of Medicine Kyoto University Kyoto Japan.
Yasuyuki AraiDepartment of Hematology Graduate School of Medicine Kyoto University Kyoto Japan.
Chisaki MizumotoDepartment of Hematology Graduate School of Medicine Kyoto University Kyoto Japan.
Toshio KitawakiDepartment of Hematology Graduate School of Medicine Kyoto University Kyoto Japan.
Kouhei YamashitaDepartment of Hematology Graduate School of Medicine Kyoto University Kyoto Japan.
Akifumi Takaori-KondoDepartment of Hematology Graduate School of Medicine Kyoto University Kyoto Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In febrile neutropenia (FN), the empirical use of anti-methicillin-resistant Objectives: To assess the impact of early administration of anti-MRSA drugs on the resolution of fever in patients undergoing allo-HCT. Methods: We retrospectively analyzed 186 allo-HCT patients. Patients receiving anti-MRSA drugs within 3 days of fever onset formed the early-decision group; those treated on or after Day 4 or untreated formed the late-decision group. Results: The early group showed a significantly shorter fever duration than the late group. ( Conclusions: Associations were observed between the timing of anti-MRSA drug administration and clinical outcomes in allo-HCT, including fever resolution and the incidence of aGVHD in older patients. Trial registration: The authors have confirmed clinical trial registration is not needed for this submission.

Indexed as

acute graft‐versus‐host diseaseallogeneic‐hematopoietic cell transplantationanti‐MRSA drugsfebrile neutropenia

Identifiers

PMID41710089
PMCPMC12910238

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.