Evidence map›Paper›PMID 41709919›Full record

Trial reportFrontiers in neurology

Effects of visually induced motor imagery-based brain-computer interface training on motor function in patients with incomplete spinal cord injury: a small-sample exploratory trial.

Yuyang Zhao, Chong Sun, Yunfeng Bi, Yongxiang Zhang

Abstract readClinical Trial
In one paragraph

Trial report in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuyang Zhao *Department of Rehabilitation Medicine, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Chong Sun *Department of Spinal Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Yunfeng BiDepartment of Rehabilitation Medicine, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Yongxiang ZhangDepartment of Rehabilitation Medicine, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to investigate the effects of visually induced motor imagery (MI)-based brain-computer interface (BCI) training on the neurological recovery of patients with incomplete spinal cord injury (iSCI), and to preliminarily explore the underlying neural mechanisms. Methods: A single-center, single-blind, small-sample exploratory trial was conducted, enrolling 11 patients with iSCI who were randomly assigned to either the experimental or control group. The experimental group received visually induced BCI training based on a MI paradigm, while the control group received visually guided MI training combined with passive lower limb movements. Both groups underwent interventions five times per week for 4 weeks. Clinical assessments, including the American Spinal Injury Association (ASIA) motor/sensory scores, Berg Balance Scale (BBS), and Functional Ambulation Category (FAC), were conducted before and after the intervention. Simultaneously, electroencephalography (EEG) data were collected to analyze brain engagement, functional connectivity, and time-frequency characteristics, aiming to elucidate the neuromodulatory effects of BCI training. Results: After the intervention, both groups showed significant improvements in brain engagement, with the experimental group demonstrating greater enhancement. Compared with before rehabilitation training, the levels of θ waves in both groups significantly increased after rehabilitation training, while the levels of β waves significantly decreased ( Conclusion: Visually induced MI-based BCI training effectively promotes neurological recovery in patients with iSCI, as evidenced by enhanced brain network reorganization, modulation of cortical excitability, and activation of motor-related neural rhythms. This study confirms the feasibility and safety of this intervention strategy and offers a novel direction for iSCI rehabilitation. Clinical Trial Registration: Chinese Clinical Trial Registry (ChiCTR), identifier: ChiCTR2400095010.

Indexed as

brain-computer interfaceEEGincomplete spinal cord injurymotor imageryneurological recovery

Identifiers

PMID41709919
PMCPMC12909217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.