ArticleJACC. Case reports2026
Bradycardia-Induced Monomorphic VT in Dilated Cardiomyopathy: Insights From ICD Upgrade Cases.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsBradycardia-induced monomorphic ventricular tachycardia (VT) is an underrecognized proarrhythmic mechanism in dilated cardiomyopathy (DCM). This case series describes patients with advanced heart failure and recurrent VT/ventricular fibrillation in whom upgrading from single- to dual-chamber implantable cardioverter-defibrillators (ICDs) provided arrhythmia suppression.
methodsThree patients with DCM, recurrent sustained VT/ventricular fibrillation, and hemodynamic instability due to bradycardia, pacing-related cycle-length variability, and loss of atrioventricular (AV) synchrony were retrospectively analyzed before and after ICD upgrade.
resultsAll patients demonstrated bradycardia-triggered monomorphic VT and clinical deterioration during ventricular pacing without AV synchrony. Upgrading to a dual-chamber system with atrial pacing corrected bradycardia, normalized cycle length, restored AV synchrony, and reduced arrhythmia burden. Two patients underwent heart transplantation under improved conditions, and 1 patient remained arrhythmia-free during long-term follow-up.
conclusionsDual-chamber ICD upgrade offers an effective strategy for preventing bradycardia-induced monomorphic VT in advanced DCM by stabilizing heart rate and eliminating proarrhythmic pacing sequences.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.