ArticleJACC. Case reports2026
Multifocal Atrial Tachycardia and Genetic Background-Guided Ablation Strategy for Atrial Fibrillation in a Young Woman.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAtrial fibrillation (AF) typically affects the elderly persons. Personalized therapy for young patients needs to be considered. CASE SUMMARY: A 28-year-old young woman presented with recurrent palpitations for over 10 years and had previously received a diagnosis of "paroxysmal AF" elsewhere. She experienced recurrence postablation and poor drug response. A repeated electrophysiological study indicated multifocal atrial tachycardia, primarily 2 types originating from the sinus venosus, and successful ablation was performed. No atrial arrhythmias were observed during 6-month postoperative follow-up. The familial predisposition was genetically confirmed, with the patient carrying a pathogenic TNNI3K gene variant. DISCUSSION: This case was challenging because of unstable activation sequences. A sequential ablation strategy targeting individual morphologies was crucial. The strong family history underscored the role of genetic testing. TAKE-HOME MESSAGES: Cautious, nonempirical management is vital for young patients with "AF". Non-pulmonary vein, embryologically categorized AF triggers should be considered. Genetics can elucidate the underlying substrate.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.