Evidence map›Paper›PMID 41709451›Full record

Observational studyPalliative & supportive care2026

Withholding and withdrawal of care in the ICU of Eastern France modalities and families feeling.

Cindy Chauchard, Antoine Goury, Bruno Lafon, Laurent Poiron, Salvatore Muccio, Magdalena Szczot, Georges Simon, Quentin Georges, Vincent Castelain, Alice Duvivier and 2 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Palliative & supportive care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cindy ChauchardAnesthesiology, Critical Care and Perioperative Medicine, University Hospital of Reims, Reims, France.
Antoine GouryMedical Intensive Care Unit, University Hospital of Reims, Reims, France.
Bruno LafonIntensive Care Unit, Polyclinique Reims-Bezannes, Bezannes, France.
Laurent PoironIntensive Care Unit, Hospital of Châlons-en-Champagne, Châlons-en-Champagne, France.
Salvatore MuccioAnesthesiology, Critical Care and Perioperative Medicine, University Hospital of Reims, Reims, France.
Magdalena SzczotDepartment of Anesthesiology and Critical Care, University Hospital of Strasbourg, Strasbourg, France.
Georges SimonIntensive Care Unit, Hospital of Troyes, Troyes, France.
Quentin GeorgesIntensive Care Unit, Hospital of Haguenau, Haguenau, France.
Vincent CastelainService de médecine intensive - réanimation, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Alice DuvivierDepartment of Clinical Research, University Hospital of Reims, Reims, France.
Lukshe KanagaratnamDepartment of Clinical Research, University Hospital of Reims, Reims, France.
Vincent LegrosAnesthesiology, Critical Care and Perioperative Medicine, University Hospital of Reims, Reims, France.ORCID https://orcid.org/0000-0002-2701-0888

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWithholding or withdrawing life-sustaining therapies (WLST) was introduced in France in 2005 through the Leonetti law to prevent futile treatments and "unreasonable obstinacy." In France, WLST decisions affect 8.5-14% of ICU patients, according to the literature. The 2016 Claeys-Leonetti law updated the previous legislation, but debates surrounding end-of-life care persist.

methodsTo describe WLST patients and practices under current legislation, we conducted a multicenter, prospective, observational study in ICUs across Eastern France. Eligible adult patients facing WLST decisions were included, requiring written consent from the patient or a trusted person. Patients were followed for 1 month. We described the decision-making process and assessed family satisfaction using the FS-24R-ICU questionnaire.

resultsBetween May 3rd and October 3rd, 2023, 73 patients were included (mean age 69 years). The majority of admissions were medical (72.7%), and 50.7% of patients had neurological impairments. ICU staff initiated WLST discussions primarily due to poor survival or quality of life prospects. Only 12.5% of patients had written advance directives, and 59.1% had designated a trusted person. External consultation was not involved in 19.1% of decisions. Families were informed in 91.7% of cases. Decisions to withhold therapies occurred in 68.1% of cases, with resuscitation during cardiac arrest being the most commonly withheld intervention (98.0%). Treatment withdrawal occurred in 31.9% of cases. Family satisfaction was generally positive.

conclusionsWLST management in Eastern French ICUs is partially compliant with the Claeys-Leonetti law. Improved law application and public awareness could enhance end-of-life care management in France.

Indexed as

FamilyWithholding TreatmentAdultAgedAged, 80 and overDecision MakingFemaleFranceHumansIntensive Care UnitsMaleMiddle AgedProspective StudiesSurveys and QuestionnairesTerminal Carefamily relationshipICUMulticenter studyobservational studywithdrawal of life-sustaining therapies

Identifiers

PMID41709451
PMCPMC13166340

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.