Evidence map›Paper›PMID 41709421›Full record

Trial reportPsychology and psychotherapy2026

Unfinished business: A grounded theory analysis of change among individuals classified as numerical non-responders to psychodynamic psychotherapy for post-traumatic stress disorder related to childhood maltreatment.

Fatima Nöske, Frederike Döring, Manfred E Beutel, Melissa Hitzler, Jürgen Hoyer, Elena Kabbathas, Christine Knaevelsrud, Iris-T Kolassa, Johannes Kruse, Falk Leichsenring and 11 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychology and psychotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Fatima NöskeInternational Psychoanalytic University Berlin, Berlin, Germany.ORCID 0009-0005-7231-3457
Frederike DöringInternational Psychoanalytic University Berlin, Berlin, Germany.
Manfred E BeutelDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center Mainz, Mainz, Germany.
Melissa HitzlerDepartment of Clinical and Biological Psychology Institute of Psychology and Education, Ulm University, Ulm, Germany.
Jürgen HoyerInstitute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany.
Elena KabbathasInternational Psychoanalytic University Berlin, Berlin, Germany.
Christine KnaevelsrudDivision of Clinical Psychological Intervention, Department of Education and Psychology, Freie Universität Berlin, Berlin, Germany.
Iris-T KolassaDepartment of Clinical and Biological Psychology Institute of Psychology and Education, Ulm University, Ulm, Germany.
Johannes KruseDepartment of Psychotherapy and Psychosomatics, Justus Liebig University Gießen, Gießen, Germany.
Falk LeichsenringDepartment of Psychotherapy and Psychosomatics, Justus Liebig University Gießen, Gießen, Germany.
Nina MarinInternational Psychoanalytic University Berlin, Berlin, Germany.
Helen NiemeyerDivision of Clinical Psychological Intervention, Department of Education and Psychology, Freie Universität Berlin, Berlin, Germany.
Simone SalzerInternational Psychoanalytic University Berlin, Berlin, Germany.
Karoline SauerDepartment of Clinical Psychology, Psychotherapy and Experimental Psychopathology, Johannes Gutenberg University Mainz, Mainz, Germany.
Marie SiebertInternational Psychoanalytic University Berlin, Berlin, Germany.
Rudolf StarkCenter for Mind, Brain and Behavior, Justus Liebig University Gießen and Philipps University Marburg, Gießen and Marburg, Germany.
Visal TumaniDepartment of Psychiatry, Ulm University, Ulm, Germany.
Kerstin WeidnerDepartment of Psychotherapy and Psychosomatic Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Jörn von WietersheimDepartment of Psychosomatic Medicine and Psychotherapy, Ulm University Medical Center, Ulm, Germany.
Wolfgang WöllerIndependent Advisor, Bonn, Germany.
Christiane SteinertInternational Psychoanalytic University Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIndividuals with post-traumatic stress disorder related to childhood maltreatment (PTSD-CM) show limited response to treatment on pre-post-symptom measures. While a nuanced understanding of nonresponse is crucial for improving treatment, quantitative measures may not fully capture clinically meaningful processes of change from the patients' perspectives. We therefore explored how individuals with PTSD-CM who showed no or limited numerical improvement after trauma-focused psychodynamic psychotherapy (TF-PDT) experienced change.

designThis qualitative study was embedded in a large randomized controlled trial on PTSD-CM (DRKS00021142).

methodFrom 75 qualitative post-treatment interviews, we purposively sampled eight TF-PDT recipients meeting criteria for numerical nonresponse, defined as current PTSD diagnosis and less than 50% reduction in the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5). Client Change Interviews were analysed using Critical-Constructivist Grounded Theory.

resultsWe derived two clusters ('Progress-A Double-Edged Sword', 'When Building Trust Collides with the Therapeutic Framework') and one overarching core category ('Unfinished Business'), which captured a dialectic process. Within a responsive therapeutic relationship, patients began confronting their relational trauma, experiencing relief, increased emotional regulation and hope. However, this very engagement surfaced emotional challenges that exceeded what could be addressed within the limited therapeutic framework, leaving the process meaningful but unfinished.

conclusionWhat is often labelled as numerical nonresponse in PTSD-CM may reflect a dynamic interplay of emerging improvement and emotional distress that needs more time to unfold. Moreover, the results underscore the value of integrating qualitative, patient-reported outcomes into treatment evaluation and relationship-focused treatment tailored to patients' individual needs.

Indexed as

Adult Survivors of Child AbusePsychotherapy, PsychodynamicStress Disorders, Post-TraumaticAdultFemaleGrounded TheoryHumansMaleMiddle AgedQualitative ResearchTreatment Effect Heterogeneitychildhood maltreatmentgrounded theorynumerical nonresponsepatient perspectivePTSDqualitativetrauma‐focused therapy

Identifiers

PMID41709421
PMCPMC13162179

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.