ArticlePlant biotechnology journal2026
VqLecRKV.4 and VqBAK1 Modulate Grapevine Resistance to Powdery Mildew by Regulating Dynamic Balance of ROS.
Article in Plant biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Grapevine powdery mildew, caused by the fungal pathogen Erysiphe necator, severely impacts plant growth and berry quality. However, the grapevine receptors and molecular mechanisms underlying grapevine resistance to E. necator remain poorly understood. In this study, we identify a G-type Lectin receptor-like kinase (LecRK), VqLecRKV.4, identified from the wild Chinese grapevine Vitis quinquangularis, whose expression is significantly upregulated in response to E. necator infection. Overexpression of VqLecRKV.4 in the susceptible cultivar V. vinifera 'Thompson Seedless' confers enhanced resistance against the pathogen, as evidenced by significantly reduced fungal colonisation and sporulation. Through TurboID-mediated proximity labelling, we demonstrate that VqLecRKV.4 interacts with VqCu/ZnSOD1. Further analysis reveals that VqLecRKV.4 promotes ROS accumulation and cell death by upregulating VqCu/ZnSOD1 expression, thereby inhibiting E. necator colonisation. A critical challenge in plant immunity is balancing immune responses to avoid overactivation. Here, we discover that VqBAK1 interacts with VqLecRKV.4 and attenuates its overreaction. Collectively, our findings reveal that the VqLecRKV.4-VqBAK1 module fine-tunes grapevine resistance to powdery mildew by maintaining ROS homeostasis, providing novel insights into the molecular mechanisms of grapevine immunity and its regulation to prevent detrimental overreaction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.