Evidence map›Paper›PMID 41708868›Full record

ArticleNature2026

Individualized mRNA vaccines evoke durable T cell immunity in adjuvant TNBC.

U Sahin, M Schmidt, E Derhovanessian, A Cortini, I Vogler, T Omokoko, E Godehardt, S Attig, S Newrzela, J Grützner and 12 more

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Towards mRNA therapeutics 2.0.Nature reviews. Drug discovery · 2026
    Review
  5. Recoding by NNature communications · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Quantitative nanoscale imaging shows peptide-MHC I complexes are monomeric and spatially regulated in human dendritic cells.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. IVT-free, chemically synthesized protein-encoding RNA oligonucleotides for rapid production of personalized cancer vaccines.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  17. Review
  18. Article
  19. Article
  20. Advances in Cancer Immunotherapy for Solid Tumors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

U Sahin *BioNTech Group, Mainz, Germany. ugur.sahin@biontech.de.ORCID 0000-0003-0363-1564
M Schmidt *Department of Obstetrics and Gynecology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.ORCID 0000-0003-1365-2414
E DerhovanessianBioNTech Group, Mainz, Germany.
A CortiniBioNTech Group, Mainz, Germany.
I VoglerBioNTech Group, Mainz, Germany.ORCID 0000-0001-9757-9618
T OmokokoBioNTech Group, Mainz, Germany.
E GodehardtBioNTech Group, Mainz, Germany.
S AttigTRON, Mainz, Germany.
S NewrzelaBioNTech Group, Mainz, Germany.
J GrütznerBioNTech Group, Mainz, Germany.
N BidmonBioNTech Group, Mainz, Germany.
S BolteBioNTech Group, Mainz, Germany.
S BrachtendorfBioNTech Group, Mainz, Germany.
T StuhlmannBioNTech Group, Mainz, Germany.
D LangerBioNTech Group, Mainz, Germany.
D BrüneBioNTech Group, Mainz, Germany.
J BlakeBioNTech Group, Mainz, Germany.
A FeldnerBioNTech Group, Mainz, Germany.
H LindmanDepartment of Immunology, Genetics and Pathology, Uppsala University Hospital, Uppsala, Sweden.ORCID 0000-0002-5871-268X
A SchneeweissDivision Gynecologic Oncology, National Center for Tumor Diseases, University Hospital and German Cancer Research Center, Heidelberg, Germany.
M EichbaumKlinik für Frauenheilkunde und Geburtshilfe, Helios Dr. Horst Schmidt Kliniken Wiesbaden, Wiesbaden, Germany.
Ö TüreciBioNTech Group, Mainz, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) is frequently associated with metastatic relapse, even at an early stage

Indexed as

Cancer VaccinesmRNA VaccinesPrecision MedicineT-LymphocytesTriple Negative Breast NeoplasmsAdultAgedAntigens, NeoplasmChemotherapy, AdjuvantFemaleHumansMiddle AgedNeoadjuvant TherapyNeoplasm Recurrence, LocalAntigens, NeoplasmCancer VaccinesmRNA Vaccines

Identifiers

PMID41708868
PMCPMC13017525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.