Evidence map›Paper›PMID 41708859›Full record

ArticleNature2026

Roles of microtubules and LIS1 in dynein transport machinery assembly.

Qinhui Rao, Jun Yang, Pengxin Chai, Steven Markus, Kai Zhang

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. AnbioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qinhui Rao *Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA. qinhui.rao@njmu.edu.cn.ORCID http://orcid.org/0000-0002-9014-9807
Jun Yang *Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-8855-8102
Pengxin ChaiDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-9702-978X
Steven MarkusDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.ORCID http://orcid.org/0000-0002-3098-0236
Kai ZhangDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA. jack.zhang@ustc.edu.cn.ORCID http://orcid.org/0000-0001-8617-2855

Funding

Project 3. IntegrationU54AI170791 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Juan Roberto Perilla Jimenez · 2022 to 2026
$30.6M
Regulation of Dynein-Mediated Transport.R35GM139483 · NIGMS · COLORADO STATE UNIVERSITY · PI Steven M Markus · 2021 to 2026
$2.9M
Structural basis of dynein-driven ciliary motilityR35GM142959 · NIGMS · YALE UNIVERSITY · PI ZHANG, KAI JACK · 2021 to 2025
$2.3M
High-throughput electron cryo-microscopeS10OD023603 · OD · YALE UNIVERSITY · PI SIGWORTH, FREDERICK J · 2018 to 2018
$1.9M
NIAID NIH HHS U54 AI170791NIGMS NIH HHS R35 GM139483NIGMS NIH HHS R35 GM142959NIH HHS S10 OD023603
6 · The paper itself

Abstract

Cytoplasmic dynein-1, a microtubule (MT)-based motor protein, requires dynactin and a coiled-coil adaptor to form the processive dynein-dynactin-adaptor (DDA) complex

Indexed as

1-Alkyl-2-acetylglycerophosphocholine EsteraseDyneinsMicrotubule-Associated ProteinsMicrotubulesAnimalsBiological TransportCryoelectron MicroscopyDynactin ComplexHumansModels, MolecularProtein Binding1-Alkyl-2-acetylglycerophosphocholine EsteraseDynactin ComplexDyneinsMicrotubule-Associated ProteinsPAFAH1B1 protein, human

Identifiers

PMID41708859
PMCPMC13133726

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.