ArticleNature2026
Single-cell and isoform-specific translational profiling of the mouse brain.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Neuron type-specific translatomes in dorsal hippocampus during early memory consolidation.Nature communications · 2026Article
- The choreography of development: RNA localization across time and space.Development (Cambridge, England) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Samantha L Sison *Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-4864-2363
Federico Zampa *Dorris Neuroscience Center, Scripps Research, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-8569-1466
Eric R Kofman *Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.
Su Yeun ChoiDorris Neuroscience Center, Scripps Research, La Jolla, CA, USA.ORCID http://orcid.org/0009-0007-2105-0890
Pratibha JagannathaDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.
Grady G NguyenCenter for RNA Technologies and Therapeutics, University of California San Diego, La Jolla, CA, USA.
Jack T NaritomiCenter for RNA Technologies and Therapeutics, University of California San Diego, La Jolla, CA, USA.
Asa ShinBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Akanksha KhorgadeBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0009-0008-0735-158X
Wenhao JinSanford Laboratories for Innovative Medicines, San Diego, CA, USA.ORCID http://orcid.org/0000-0002-7885-3527
Chun-Yuan ChenSanford Stem Cell Institute Innovation Center, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-6212-2888
David M SievertDorris Neuroscience Center, Scripps Research, La Jolla, CA, USA.
Sourish MukhopadhyayDorris Neuroscience Center, Scripps Research, La Jolla, CA, USA.
Orel MizrahiDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.
Steven M BlueDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-0279-6690
Ryan J MarinaDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-2427-7912
Dong YangDorris Neuroscience Center, Scripps Research, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-0612-1439
Cailynn C WangDorris Neuroscience Center, Scripps Research, La Jolla, CA, USA.
Zhengyuan PangDorris Neuroscience Center, Scripps Research, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-0321-4891
Kristopher W BrannanHouston Methodist Research Institute, Houston, TX, USA.
Li YeDorris Neuroscience Center, Scripps Research, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-3077-802X
Aziz M Al'KhafajiBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-4677-5667
Gene W YeoDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA. geneyeo@ucsd.edu.ORCID http://orcid.org/0000-0002-0799-6037
Giordano LippiDorris Neuroscience Center, Scripps Research, La Jolla, CA, USA. glippi@scripps.edu.ORCID http://orcid.org/0000-0003-3911-0525
Funding
Functional RNA elements in the human genomeR01HG004659 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Kevin Daniel Corbett, Eugene Wei-Ming Yeo · 2008 to 2026
$12.4MA Comprehensive Functional Map of Human Protein-RNA InteractionsU41HG009889 · NHGRI · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI GRAVELEY, BRENTON R., YEO, EUGENE WEI-MING · 2018 to 2021
$9.4MTherapeutic strategies for microsatellite expansion diseases using RNA-targeting CRISPR/CasR01NS103172 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MAURICE SCOTT SWANSON, Eugene Wei-Ming Yeo · 2017 to 2026
$5.6MA comprehensive binding and functional map of human RNA-binding proteinsU24HG009889 · NHGRI · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI GRAVELEY, BRENTON R., YEO, EUGENE WEI-MING · 2022 to 2025
$5.5MSTAMP technology to enable single-cell and isoform-sensitive detection of RBP sitesR01HG011864 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI YEO, EUGENE WEI-MING · 2021 to 2024
$4.0MUltra low-input epigenetic sequencing with combined enzymatic and long-read technologiesR01HG010646 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI Gang Fang, Rahul Manu Kohli · 2019 to 2026
$3.9MExperience-dependent Cellular Plasticity MechanismsR01EY031597 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI CLINE, HOLLIS T. · 2021 to 2025
$3.6MBeyond Transcription - microRNA Regulation of Neuronal DevelopmentR01NS121223 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI LIPPI, GIORDANO · 2021 to 2025
$3.5MMapping brain-wide opioid actions by profiling neuronal activities and in vivo cellular target engagementR01DA059393 · NIDA · SCRIPPS RESEARCH INSTITUTE, THE · PI Laura M. Bohn, Ryan Ashok Shenvi · 2023 to 2026
$3.3MRibo-STAMPEDE: novel tools for molecular profiling of brain cell typesRF1MH126719 · NIMH · SCRIPPS RESEARCH INSTITUTE, THE · PI LIPPI, GIORDANO, YEO, EUGENE WEI-MING · 2022 to 2022
$2.3MNEI NIH HHS R01 EY031597NHGRI NIH HHS R01 HG004659NHGRI NIH HHS R01 HG010646NHGRI NIH HHS R01 HG011864NHGRI NIH HHS U24 HG009889NHGRI NIH HHS U41 HG009889NIDA NIH HHS R01 DA059393NIMH NIH HHS RF1 MH126719NINDS NIH HHS R01 NS103172NINDS NIH HHS R01 NS121223
Abstract
The brain displays the richest repertoire of post-transcriptional mechanisms regulating mRNA translation
Indexed as
BrainProtein BiosynthesisSingle-Cell AnalysisAlternative SplicingAnimalsCA1 Region, HippocampalCA3 Region, HippocampalFemaleGene Expression ProfilingHippocampusMaleMiceMice, Inbred C57BLNeuronsOrgan SpecificityProtein IsoformsProtein IsoformsRNA, Messenger
Identifiers
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.