Evidence map›Paper›PMID 41708851›Full record

ArticleNature2026

Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor.

Kathryn E Appler, James P Lingford, Xianzhe Gong, Kassiani Panagiotou, Pedro Leão, Marguerite V Langwig, Chris Greening, Thijs J G Ettema, Valerie De Anda, Brett J Baker

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. The archaeal roots of eukaryotic life.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Quantum Effects in Evolution: Terrestrial Fine-Tuning of Magnetic Parameters.Computational and structural biotechnology journal · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kathryn E ApplerDepartment of Marine Science, Marine Science Institute, University of Texas at Austin, Port Aransas, TX, USA.ORCID 0000-0002-1219-1786
James P LingfordDepartment of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.
Xianzhe GongDepartment of Marine Science, Marine Science Institute, University of Texas at Austin, Port Aransas, TX, USA.
Kassiani PanagiotouLaboratory of Microbiology, Wageningen University and Research, Wageningen, The Netherlands.ORCID 0009-0006-1191-7326
Pedro LeãoDepartment of Marine Science, Marine Science Institute, University of Texas at Austin, Port Aransas, TX, USA.ORCID 0000-0001-5386-7626
Marguerite V LangwigDepartment of Marine Science, Marine Science Institute, University of Texas at Austin, Port Aransas, TX, USA.ORCID 0000-0002-0247-2816
Chris GreeningDepartment of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.ORCID 0000-0001-7616-0594
Thijs J G EttemaLaboratory of Microbiology, Wageningen University and Research, Wageningen, The Netherlands.ORCID 0000-0002-6898-6377
Valerie De AndaDepartment of Marine Science, Marine Science Institute, University of Texas at Austin, Port Aransas, TX, USA.
Brett J BakerDepartment of Marine Science, Marine Science Institute, University of Texas at Austin, Port Aransas, TX, USA. brett_baker@utexas.edu.ORCID 0000-0002-5971-1021

Funding

Dutch Research CouncilNational Natural Science Foundation of China
6 · The paper itself

Abstract

Asgard archaea were pivotal in the origin of complex cellular life

Indexed as

ArchaeaEukaryotaOxygenAerobiosisGenome, ArchaealGeologic SedimentsHemeMetagenomeOrigin of LifePhylogenyReactive Oxygen SpeciesHemeOxygenReactive Oxygen Species

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.