ArticleNature2026
In vivo base editing of Chd3 rescues behavioural abnormalities in mice.
RetractedAbstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Ensuring safety and accountability in China's biomedical translation system.Nature biotechnology · 2026Article
- Article
Corrections and comments
- Expression of concern · 2026-07-29Concerns/Issues about Data · Investigation by Journal/Publisher · · see also: https://pubpeer.com/publications/F43E5C3E3337419DD5C90498044690
Authors and funding
33 authors.
Kan Yang *Department of Developmental and Behavioral Pediatric and Child Primary Care, Brain and Behavioral Research Unit of Shanghai Institute for Pediatric Research and MOE-Shanghai Key Laboratory for Children's Environmental Health of Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. kanyang@shsmu.edu.cn.ORCID http://orcid.org/0000-0003-1563-1406
Wei-Ke Li *Institute of Pediatrics, National Children's Medical Center, Children's Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China.
Yi-Xiao Geng *Department of Neurology, Songjiang Hospital, Songjiang Research Institute, State Key Laboratory of Eye Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0009-0005-9685-504X
Shu-Qian Zhang *Department of Pediatrics, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID http://orcid.org/0000-0001-8858-7771
Shi-Hao Wu *School of Medicine, Yunnan University, Kunming, China.
Yan-Bo Cheng *State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Jun-Wen WangDepartment of Neurology, Songjiang Hospital, Songjiang Research Institute, State Key Laboratory of Eye Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhan-Kui XuCollege of Materials and Chemical Engineering, Hunan Institute of Engineering, Xiangtan, China.
Wen-Xin WangDepartment of Neurology, Songjiang Hospital, Songjiang Research Institute, State Key Laboratory of Eye Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tan-Ying ZhangCollege of Materials and Chemical Engineering, Hunan Institute of Engineering, Xiangtan, China.
Pei-Ye WangDepartment of Neurology, Songjiang Hospital, Songjiang Research Institute, State Key Laboratory of Eye Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yi-Ting YuanDepartment of Neurology, Songjiang Hospital, Songjiang Research Institute, State Key Laboratory of Eye Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Juan FanCollege of Materials and Chemical Engineering, Hunan Institute of Engineering, Xiangtan, China.
Jun WuDepartment of Neurology, Songjiang Hospital, Songjiang Research Institute, State Key Laboratory of Eye Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ruo-Chuan XuCollege of Basic Medical Science, Shanghai Jiao Tong University School of medicine, Shanghai, China.
Yue-Fang ZhangDepartment of Neurology, Songjiang Hospital, Songjiang Research Institute, State Key Laboratory of Eye Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Gong-Jia TaoDepartment of Neurology, Songjiang Hospital, Songjiang Research Institute, State Key Laboratory of Eye Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zheng-Hui LiQianweichang College, Shanghai University, Shanghai, China.ORCID http://orcid.org/0009-0005-1761-6383
Chen-Xi LinCollege of Basic Medical Science, Shanghai Jiao Tong University School of medicine, Shanghai, China.
Tian-Shu LiDepartment of Neurology, Songjiang Hospital, Songjiang Research Institute, State Key Laboratory of Eye Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xin-Yi ZhangInstitute of Pediatrics, National Children's Medical Center, Children's Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China.
Jie LiInstitute of Pediatrics, National Children's Medical Center, Children's Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China.
Ru ZhangCollege of Materials and Chemical Engineering, Hunan Institute of Engineering, Xiangtan, China.
Wen-Xiu YangSchool of Medicine, Yunnan University, Kunming, China.
Jia-Shuo WenSchool of Medicine, Yunnan University, Kunming, China.
Zun-Yuan YangPriMed Non-human Primate Research Center, Sichuan PriMed Shines Bio-tech, Ya'an, China.
Li GongPriMed Non-human Primate Research Center, Sichuan PriMed Shines Bio-tech, Ya'an, China.
Wen ZengPriMed Non-human Primate Research Center, Sichuan PriMed Shines Bio-tech, Ya'an, China.
Ai-Lian DuDepartment of Neurology, Songjiang Hospital, Songjiang Research Institute, State Key Laboratory of Eye Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jin-Song LiState Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0000-0003-3456-662X
Fei LiDepartment of Developmental and Behavioral Pediatric and Child Primary Care, Brain and Behavioral Research Unit of Shanghai Institute for Pediatric Research and MOE-Shanghai Key Laboratory for Children's Environmental Health of Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. feili@shsmu.edu.cn.ORCID http://orcid.org/0000-0002-2455-4986
Tian-Lin ChengInstitute of Pediatrics, National Children's Medical Center, Children's Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China. chengtianlin@fudan.edu.cn.ORCID http://orcid.org/0000-0003-0680-6710
Zilong QiuDepartment of Developmental and Behavioral Pediatric and Child Primary Care, Brain and Behavioral Research Unit of Shanghai Institute for Pediatric Research and MOE-Shanghai Key Laboratory for Children's Environmental Health of Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. qiuzilong@shsmu.edu.cn.ORCID http://orcid.org/0000-0003-4286-3288
Funding
National Science and Technology Major ProjectProject of Medical Technology Research and Transformation supported by Shanghai Municipal Health CommissionYouth Innovation Promotion Association Chinese Academy of Sciences
Abstract
Neurodevelopmental disorders that arise from de novo mutations in chromatin-remodelling genes lack targeted treatments. Snijders Blok-Campeau syndrome (SNIBCPS)
Indexed as
Behavior, AnimalDNA-Binding ProteinsDNA HelicasesGene EditingGenetic TherapyAnimalsBrainCognitionDependovirusDisease Models, AnimalFemaleHippocampusHumansIntellectual DisabilityMaleMiceDNA-Binding ProteinsDNA Helicases
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.