Evidence map›Paper›PMID 41708707›Full record

ArticleScientific reports2026

Integrative framework for cancer detection via integro-differential equations using deep learning techniques.

Tanneeru Gopisairam, Srinivasarao Thota, Thulasi Bikku

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tanneeru GopisairamDepartment of Mathematics, Amrita School of Physical Sciences, Amrita Vishwa Vidyapeetham, Amaravati, Andhra Pradesh, 522503, India.
Srinivasarao ThotaDepartment of Mathematics, Amrita School of Physical Sciences, Amrita Vishwa Vidyapeetham, Amaravati, Andhra Pradesh, 522503, India. t_srinivasarao@av.amrita.edu.
Thulasi BikkuDepartment of Computer Science and Engineering, Amrita School of Computing, Amrita Vishwa Vidyapeetham, Amaravati, Andhra Pradesh, 522503, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer diagnosis remains challenging in clinical practice, motivating the development of computational tools for accurate identification of cancerous regions in medical images. Recent advances in deep learning have shown potential to support these tasks. This study proposes a framework that converts 2D medical images (e.g., mammograms) into 1D signals for efficient feature extraction, followed by classification using a 1D convolutional neural network. Integro-differential equations are incorporated to model tumor growth dynamics and spatial-temporal intensity variations, with the goal of improving interpretability. The approach was evaluated on publicly available mammography datasets (INbreast and MIAS). In preliminary experiments, it achieved 96.4% accuracy in binary classification, comparable to or slightly better than selected conventional deep learning baselines on these benchmarks. The paper discusses advantages in feature extraction and computational aspects, along with limitations related to data dependency, information loss during signal conversion, and simplifications in the mathematical models.

Indexed as

Breast NeoplasmsDeep LearningImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedAlgorithmsConvolutional Neural NetworksFemaleHumansMammographyCancer detectionDifferential equationsExplainable AIImage processingSegmentationTransfer learning

Identifiers

PMID41708707
PMCPMC13013581

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.