Evidence map›Paper›PMID 41708693›Full record

ArticleScientific reports2026

Potential biomarkers for early periodontal inflammation: investigating CD5

Elisabeth Clara Gottschalk, Oleksandra Chabanovska, Praveen Vasudevan, Israel Barrantes, Bernd Kreikemeyer, Wendy Bergmann-Ewert, Robby Engelmann, Brigitte Müller-Hilke, Hermann Lang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Periodontal health and disease.Scientific reports · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elisabeth Clara Gottschalk *Department of Operative Dentistry and Periodontology, University Medical Center Rostock, Rostock, Germany.
Oleksandra Chabanovska *Department of Operative Dentistry and Periodontology, University Medical Center Rostock, Rostock, Germany. oleksandra.chabanovska@med.uni-rostock.de.
Praveen VasudevanDepartment of Operative Dentistry and Periodontology, University Medical Center Rostock, Rostock, Germany.
Israel BarrantesResearch Group Translational Bioinformatics, Institute for Biostatistics and Informatics in Medicine and Ageing Research, University Medical Center Rostock, Rostock, Germany.
Bernd KreikemeyerInstitute of Medical Microbiology, Virology and Hygiene, University Medical Center Rostock, Rostock, Germany.
Wendy Bergmann-EwertCore Facility for Cell Sorting and Cell Analysis, University Medical Center Rostock, Rostock, Germany.
Robby EngelmannCore Facility for Cell Sorting and Cell Analysis, University Medical Center Rostock, Rostock, Germany.
Brigitte Müller-HilkeCore Facility for Cell Sorting and Cell Analysis, University Medical Center Rostock, Rostock, Germany.
Hermann LangDepartment of Operative Dentistry and Periodontology, University Medical Center Rostock, Rostock, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis is a highly prevalent chronic inflammatory disease that causes progressive destruction of the tooth-supporting apparatus and is linked to multiple systemic disorders. Despite its high prevalence, early biomarkers capable of predicting individual susceptibility remain elusive. The multifactorial nature of the disease and the lack of a validated, specific indicators hinder reliable early diagnosis before irreversible tissue damage occurs. CD5

Indexed as

B-LymphocytesCD5 AntigensCytokinesMicrobiotaPeriodontitisSalivaAdultBiomarkersCross-Sectional StudiesFemaleHumansInterleukin-17MaleMiddle AgedBiomarkersCD5 AntigensCytokinesInterleukin-17CD5+ B cellsCytokinesOral microbiomePeriodontal healthPeriodontitis

Identifiers

PMID41708693
PMCPMC12920879

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.