Evidence map›Paper›PMID 41708516›Full record

ArticleRenal failure2026

Four-organ SOFA score as a potential tool to triage use of continuous kidney replacement therapy in COVID-19 patients with acute kidney injury: a retrospective two-center study.

Fatemeh Abbasi, Tomonori Takeuchi, Gabriela M Orellana, David Perez Ingles, Zachary Bruss, Chandra Kodavanti, Lisa Saa, Alisa C Illescas, Jonathan L Marinaro, Michelle S Harkins and 2 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Renal failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fatemeh AbbasiDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico (UNM) School of Medicine, Albuquerque, NM, USA.
Tomonori TakeuchiDivision of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Gabriela M OrellanaDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico (UNM) School of Medicine, Albuquerque, NM, USA.
David Perez InglesDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico (UNM) School of Medicine, Albuquerque, NM, USA.
Zachary BrussDepartment of Internal Medicine, UNM School of Medicine, Albuquerque, NM, USA.
Chandra KodavantiDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico (UNM) School of Medicine, Albuquerque, NM, USA.
Lisa SaaDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico (UNM) School of Medicine, Albuquerque, NM, USA.
Alisa C IllescasDepartment of Internal Medicine, UNM School of Medicine, Albuquerque, NM, USA.
Jonathan L MarinaroDepartment of Emergency Medicine, UNM School of Medicine, Albuquerque, NM, USA.
Michelle S HarkinsDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico (UNM) School of Medicine, Albuquerque, NM, USA.
Christos P ArgyropoulosDivision of Nephrology, Department of Internal Medicine, UNM School of Medicine, Albuquerque, NM, USA.
J Pedro TeixeiraDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico (UNM) School of Medicine, Albuquerque, NM, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury requiring continuous kidney replacement therapy (AKI-CKRT) in the setting of coronavirus disease 2019 (COVID-19) carries a high mortality. In this two-center retrospective cohort study, we analyzed whether a simplified Sequential Organ Failure Assessment (SOFA) score, the 4-organ SOFA score with renal and neurologic sub-scores removed, would perform as well as the full SOFA score in predicting mortality. In our primary cohort, we identified 63 patients with COVID-19 hospitalized in April 2020 to July 2021 with AKI-CKRT and determined their 4-organ and full SOFA scores at CKRT initiation. Thirty-day and in-hospital mortality were 73.0% and 82.5%, respectively. The median 4-organ SOFA score at CKRT initiation among 30-day survivors was 7 (interquartile range 5.5-8.5) versus 8 (7-10) among 30-day non-survivors (

Indexed as

Acute Kidney InjuryContinuous Renal Replacement TherapyCOVID-19Organ Dysfunction ScoresTriageAgedFemaleHospital MortalityHumansMaleMiddle AgedPrognosisRetrospective StudiesSARS-CoV-2acute kidney injuryCOVID-19CRRTpandemic triageSOFA score

Identifiers

PMID41708516
PMCPMC12918399

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.