Evidence map›Paper›PMID 41708054›Full record

ArticleACS biomaterials science & engineering2026

Injectable

Lisa Schöbel, Juri Artes, Markus Lorke, Aldo R Boccaccini

Abstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lisa SchöbelInstitute of Biomaterials, Department of Materials Science and Engineering, Friedrich Alexander-University Erlangen-Nuremberg, 91056 Erlangen, Germany.ORCID 0000-0003-0391-4089
Juri ArtesInstitute of Biomaterials, Department of Materials Science and Engineering, Friedrich Alexander-University Erlangen-Nuremberg, 91056 Erlangen, Germany.
Markus LorkeInstitute of Biomaterials, Department of Materials Science and Engineering, Friedrich Alexander-University Erlangen-Nuremberg, 91056 Erlangen, Germany.
Aldo R BoccacciniInstitute of Biomaterials, Department of Materials Science and Engineering, Friedrich Alexander-University Erlangen-Nuremberg, 91056 Erlangen, Germany.ORCID 0000-0002-7377-2955

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study introduces an injectable oxidized alginate-gelatin hydrogel system for cartilage tissue engineering, employing a combination of covalent and noncovalent cross-linking mechanisms. Specifically, the network is formed through Schiff's Base reactions alongside enzymatic and ionic cross-linking. The hydrogels were investigated regarding their mechanical properties, swelling and degradation behavior, injectability, and cytocompatibility. The results indicated tailorable mechanical properties with an effective modulus ranging from 12 to 20 kPa, depending on the enzymatic cross-linker concentration, while demonstrating suitable injectability required for clinical applications with injection forces in the range of 3-5 N. Moreover, the syringe-mixing approach of

Indexed as

AlginatesCartilageGelatinHydrogelsTissue EngineeringAnimalsBiocompatible MaterialsCell LineChondrocytesCross-Linking ReagentsGlucuronic AcidHexuronic AcidsMiceOxidation-ReductionTissue ScaffoldsAlginatesBiocompatible MaterialsCross-Linking ReagentsGelatinGlucuronic AcidHexuronic AcidsHydrogelsalginatecartilage tissue engineeringgelatininjectable hydrogelin situ cross-linking

Identifiers

PMID41708054
PMCPMC12976994

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.