Evidence map›Paper›PMID 41707615›Full record

ArticleRedox biology2026

Endothelial cystathionine-γ-lyase (CTH) regulates body weight and insulin resistance in mice fed a high-fat diet.

Takashi Yagi, Shafiul Alam, Saima I Niti, Sibile Pardue, Xinggui Shen, John D Glawe, Gopi K Kolluru, Tomohiro Tanaka, Christopher G Kevil

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Redox biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Takashi YagiDepartment of Pathology and Translational Pathobiology, LSU Health Sciences Center, Shreveport, Louisiana, USA.
Shafiul AlamDepartment of Pathology and Translational Pathobiology, LSU Health Sciences Center, Shreveport, Louisiana, USA.
Saima I NitiDepartment of Cellular Biology and Anatomy, LSU Health Sciences Center, Shreveport, Louisiana, USA.
Sibile PardueDepartment of Pathology and Translational Pathobiology, LSU Health Sciences Center, Shreveport, Louisiana, USA.
Xinggui ShenDepartment of Pathology and Translational Pathobiology, LSU Health Sciences Center, Shreveport, Louisiana, USA.
John D GlaweDepartment of Pathology and Translational Pathobiology, LSU Health Sciences Center, Shreveport, Louisiana, USA.
Gopi K KolluruDepartment of Pathology and Translational Pathobiology, LSU Health Sciences Center, Shreveport, Louisiana, USA.
Tomohiro TanakaDepartment of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, Nagoya, Japan.
Christopher G KevilDepartment of Pathology and Translational Pathobiology, LSU Health Sciences Center, Shreveport, Louisiana, USA; Department of Cellular Biology and Anatomy, LSU Health Sciences Center, Shreveport, Louisiana, USA; Department of Molecular and Cellular Physiology, LSU Health Sciences Center, Shreveport, Louisiana, USA. Electronic address: chris.kevil@lsuhs.edu.

Funding

Stress Exacerbates Myocardial Ischemic Injury by Blocking Estrogen's Antidoxidant Protection in the Female HeartP20GM121307 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI Gopi K Kolluru · 2018 to 2026
$23.6M
NHLBI NIH HHS HL 149264NIH P20GM121307
6 · The paper itself

Abstract

Hydrogen sulfide (H

Indexed as

Body WeightCystathionine gamma-LyaseDiet, High-FatInsulin ResistanceAdipose TissueAdipose Tissue, WhiteAnimalsChemokine CCL2Energy MetabolismGlucoseGlucose Transporter Type 4InsulinMaleMiceMice, KnockoutMuscle, SkeletalChemokine CCL2Cystathionine gamma-LyaseGlucoseGlucose Transporter Type 4InsulinUncoupling Protein 1

Identifiers

PMID41707615
PMCPMC12926982

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.