Trial reportAmerican journal of physical medicine & rehabilitation2026
At-Home Delivery of Vagus Nerve Stimulation Paired With Task-Specific Training Improves Performance of High-Priority Activities in Persons With Chronic Spinal Cord Injury or Stroke.
Trial report in American journal of physical medicine & rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Auricular Vagus Nerve Stimulation Combined with Physical Therapy for Individuals with Parkinson's Disease: A Pilot Randomized Sham-Controlled Trial.Neurology international · 2026Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
objectiveVagus nerve stimulation during rehabilitative training can improve motor function years after stroke or spinal cord injury. This open-label study examined whether vagus nerve stimulation paired with participant-selected activities of daily living in a home environment can improve task performance in participants with chronic stroke or incomplete cervical spinal cord injury.
designFourteen participants were recruited from our previous randomized studies involving months of vagus nerve stimulation delivered during in-clinic therapy. Seven participants with chronic stroke and seven with chronic incomplete spinal cord injury completed 36 additional sessions of vagus nerve stimulation paired with training on a set of self-selected, high-priority activities of daily living at home. Each participant trained on 5-10 tasks. Performance was measured before and after vagus nerve stimulation + ADL therapy.
resultsVagus nerve stimulation + activity of daily living therapy reduced time to complete trained activities of daily living by 19.8 ± 5.2% for participants with stroke and 33.8 ± 4.9% for participants with spinal cord injury.
conclusionsThe observed gains are clinically meaningful and suggest a reduction in the functional burden of injury, which has the potential to improve independence and reduce reliance on caregivers. These initial results are sufficient to justify a randomized, sham-controlled study to evaluate whether vagus nerve stimulation during task-specific training can improve task performance and independence.
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