Evidence map›Paper›PMID 41707071›Full record

SynthesisEcology letters2026

The Evolution and Ecology of Host Manipulation in Helminth Parasites: A Phylogenetic Meta-Analysis.

Nina Hafer-Hahmann

Abstract readMeta-Analysis
In one paragraph

Synthesis in Ecology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Nina Hafer-HahmannDepartment of Biology, University of Konstanz, Konstanz, Germany.ORCID https://orcid.org/0000-0002-6645-0149

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parasites have repeatedly evolved the ability to modify their host's behaviour to enhance transmission. However, the conditions shaping such host manipulation remain unclear. I conducted a phylogenetic meta-analysis of 207 studies comprising 1635 observations from 82 parasite and 80 host taxa to identify patterns in host manipulation and test ecological and evolutionary drivers of host manipulation in trophically transmitted helminths. Manipulation reliably increased host susceptibility to predation and effects depended strongly on parasite stage: mature parasites consistently enhanced predation susceptibility, whereas immature stages showed little or inconsistent impact. In mixed infections, mature parasites dominated, and manipulation was stronger in the presence of the correct predator. Phylogenetic constraints were minimal, in line with repeated independent origins. The ecological and evolutionary drivers and constraints tested here had only weak or inconsistent effects.

Indexed as

Biological EvolutionHelminthsHost-Parasite InteractionsPhylogenyAnimalscomplex life cycleevolutionextended phenotypehelminthshost behaviourhost manipulationhost–parasite interactionsmeta‐analysistrophic transmission

Identifiers

PMID41707071
PMCPMC12916080

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.