ArticleVeterinary medicine and science2026
Susceptibility of Gecko Cell Line for Cultivation and Adaptation of Infectious Bursal Disease Virus as an Experimental Vaccine.
Article in Veterinary medicine and science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Nowadays, vaccination is the primary and most effective method for preventing and controlling Infectious bursal disease virus (IBDV). A study examined the potential of a new Gecko cell line (Z1) for cultivating IBDV due to evolutionary similarities between birds and reptiles. After observing complete cytopathic effects (CPE), virus titre was determined using the TCID50 assay, and viral replication was confirmed using an RT-PCR test. In the next step, 150 broiler chickens (15 days old) were randomly divided into three equal groups for immune response measurements: G1: immunized/commercial vaccine, G2: immunized/experimental vaccine and G3: control. Antibody responses and the bursal index were evaluated on different days post-immunization. On the basis of the results, CPE of the virus was noticeable from the first passage, becoming complete by the second passage, and an infectious titre of the virus was 10
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