Evidence map›Paper›PMID 41706859›Full record

ArticleScience advances2026

Transmembrane proteins mediate basal complex assembly and individual daughter cell formation in malaria parasites.

Peter S Back, Erinn Wagner, Paula Montero Llopis, Ramon G de Oliveira, Marco Mottinelli, Lori Ferrins, Jeffrey D Dvorin

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peter S BackDivision of Infectious Diseases, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0002-4653-8602
Erinn WagnerDivision of Infectious Diseases, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0009-0009-9009-2298
Paula Montero LlopisMicRoN Core, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-5983-2296
Ramon G de OliveiraInstitute of Chemistry, State University of Campinas, Campinas 13083-862, Brazil.ORCID 0000-0002-2407-5766
Marco MottinelliChemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0001-5725-0439
Lori FerrinsChemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0001-8992-0919
Jeffrey D DvorinDivision of Infectious Diseases, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0002-5883-7271

Funding

Understanding the role of transmembrane proteins for Plasmodium cell divisionF32AI186297 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI Peter S Back · 2024 to 2026
$151k
NIAID NIH HHS F32 AI186297
6 · The paper itself

Abstract

Asexual reproduction of malaria parasites requires the basal complex, the equivalent of a eukaryotic contractile ring. Despite its central role, basal complex biogenesis remains largely unknown. Here, we use expansion microscopy and DNA points accumulation for imaging in nanoscale topography to investigate three transmembrane basal complex proteins in

Indexed as

Membrane ProteinsPlasmodium falciparumProtozoan ProteinsCell DivisionCell MembraneMembrane ProteinsProtozoan Proteins

Identifiers

PMID41706859
PMCPMC12915615

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.