Evidence map›Paper›PMID 41706406›Full record

SynthesisDigestive diseases and sciences2026

Outcomes of Repeat Endoscopic Retrograde Cholangiopancreatography Following Initial Unsuccessful Cannulation: A Systematic Review and Meta-Analysis.

Alejandra Tepox-Padrón, Badal S B Pattar, Douglas G Adler, Daniel Niven, Nauzer Forbes

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alejandra Tepox-PadrónDivision of Community Health Sciences, University of Calgary, Calgary, AB, Canada.
Badal S B PattarLibin Cardiovascular Institute, University of Calgary, Calgary, AB, Canada.
Douglas G AdlerPorter Adventist Hospital, Advent Health, Denver, CO, USA.
Daniel NivenDivision of Community Health Sciences, University of Calgary, Calgary, AB, Canada.
Nauzer ForbesDivision of Community Health Sciences, University of Calgary, Calgary, AB, Canada. nauzer.forbes@ucalgary.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsEndoscopic retrograde cholangiopancreatography (ERCP) is commonly used to treat pancreaticobiliary diseases, but can be technically challenging, leading to occasional unsuccessful attempts. While repeat ERCP is one option in these cases, data on the effectiveness and safety of this practice remain limited. Thus, we conducted a systematic review and meta-analysis to assess outcomes of repeat ERCP after initial unsuccessful attempt.

methodsMEDLINE, Embase, and CENTRAL were searched on February 28, 2025. We included randomized trials and observational studies reporting on outcomes of repeat ERCP following an initial unsuccessful attempt, with the primary outcome being technical success of cannulation, and secondary outcomes including adverse events (AEs). Random-effects models were used to pool data, and heterogeneity was assessed through the I

resultsA total of 22 studies involving 1514 patients with a median age of 62 years were included. The majority of studies were conducted at a single center (86.4%), where the most common indication for repeat ERCP was choledocholithiasis (41.2%), followed by malignant biliary obstruction (29.0%). The pooled technical success rate of repeat ERCP was 83.6% (95% CI 78.6-88.1%, I

conclusionsOur meta-analysis demonstrated encouraging success rates with repeat ERCP after initial failure, with acceptably low AE rates, highlighting its role as a primary option in cases of initial unsuccessful ERCP.

Indexed as

CatheterizationCholangiopancreatography, Endoscopic RetrogradeHumansReoperationTreatment OutcomeAdverse eventsEndoscopic qualityEndoscopic retrograde cholangiopancreatography

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.