Evidence map›Paper›PMID 41706271›Full record

ArticleScience China. Life sciences2026

The risk of pathogenic tick-borne viruses in Northeast Asia: a genomic and ecological modelling study.

Moujian Guo, Hengcong Liu, Hong Zhou, Xiurong Wang, Xudong Zhang, Yu Cao, Jiaqi Qin, Qian Zhang, Weixue Wang, Wen Zheng and 9 more

Abstract read
PubMed Publisher
In one paragraph

Article in Science China. Life sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Moujian Guo *Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Hengcong Liu *Shanghai Institute of Virology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Hong Zhou *School of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250117, China.
Xiurong WangSchool of Basic Medicine, Guizhou Medical University, Anshun, 561000, China.
Xudong ZhangShandong Public Health Clinical Center, Shandong University, Jinan, 250000, China.
Yu CaoSchool of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250117, China.
Jiaqi QinSchool of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250117, China.
Qian ZhangSchool of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250117, China.
Weixue WangShanghai Institute of Virology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Wen ZhengShanghai Institute of Virology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Renyan JiAlongshan Forest Fire Prevention Station, China Inner Mongolia Forest Industry Group Alongshan Forest Industry Co., Ltd., Hulunbuir, 021000, China.
Yunxiao WangShanghai Institute of Virology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Shang QiDalian Center for Disease Control and Prevention, Dalian, 116000, China.
Lei YuDalian Center for Disease Control and Prevention, Dalian, 116000, China.
Xingying LangDalian Center for Disease Control and Prevention, Dalian, 116000, China.
Edward C HolmesSchool of Medical Sciences, The University of Sydney, Sydney, NSW, 2006, Australia.
Guoqing WangCollege of Basic Medical Sciences, Jilin University, Changchun, 130021, China. qing@jlu.edu.cn.
Quan LiuDepartment of Infectious Diseases and Center of Infectious Diseases and Pathogen Biology, Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis of the Ministry of Education, The First Hospital of Jilin University, Changchun, 130021, China. quanliu@jlu.edu.cn.
Weifeng ShiRuijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. shiwf@ioz.ac.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence, epidemiological history and disease risk posed by pathogenic tick-borne viruses (TBVs) remain poorly understood in Northeast Asia. Here, over 12,000 ticks were collected from diverse ecological environments in Northeast China, leading to the identification of 44 TBVs from which 1,221 viral sequences were assembled. This included six human/mammal-infecting TBVs: Alongshan virus, Beiji nairovirus, Mukawa virus, Nuomin virus, tick-borne encephalitis virus (TBEV), and Yezo virus. Aga, Izumo, and Nishinomiya in Japan were identified as tick diversity hotspots, while Shangzhi City, Genhe City, and Raohe County in China were classified as TBV hotspots. We then performed an ecological modelling of seven human-infecting TBVs and their major tick species. Both TBVs and their tick vectors were projected to have a wider distribution potential than previously recognized, including the human-infecting Wetland virus (WELV) identified in 2024. Notably, aside from WELV, the other six human-infecting TBVs were predicted to circulate in all five Northeast Asian countries. Specifically, severe fever with thrombocytopenia syndrome virus was projected to potentially impact 266.74 million people, including nearly 100% of the population of Liaoning of China, the Republic of Korea (ROK) and the Democratic People's Republic of Korea (DPRK), and 91.6% of the Japanese population. TBEV was modelled to have the widest distribution potential area of 8.56 million km

Indexed as

Tick-Borne DiseasesTicksAnimalsChinaGenomicsHumansecological modellingemerging infectious diseasesNortheast AsiaNortheast Chinarisk assessmentsevere fever with thrombocytopenia syndrome virustick-borne encephalitis virustick-borne viruses

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.