Evidence map›Paper›PMID 41706215›Full record

ReviewSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Cancer-related fatigue in cancer survivors: an updated clinical practice review for healthcare providers.

Jashmira K Bhinder, Daniel Astray, Samantha K F Kennedy, Malika Peera, Shing Fung Lee, Edward Chow, Henry C Y Wong, Darren Haywood, Nicolas H Hart, Muna Al-Khaifi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jashmira K BhinderFaculty of Health Sciences, Queen's University, Kingston, ON, Canada.
Daniel AstraySchulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Samantha K F KennedyDepartment of Family and Community Medicine, Odette Cancer Centre, University of Toronto, Toronto, Canada.
Malika PeeraFaculty of Health Sciences, Queen's University, Kingston, ON, Canada.
Shing Fung LeeDepartment of Radiation Oncology, National University Cancer Institute, National University , Hospital, Singapore.
Edward ChowDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Henry C Y WongDepartment of Oncology, Princess Margaret Hospital, Kowloon West Cluster, Hong Kong S.A.R., Kowloon, China.
Darren HaywoodHuman Performance Research Centre, INSIGHT Research Institute, Faculty of Health, University of Technology Sydney (UTS), Sydney, NSW, Australia.
Nicolas H HartHuman Performance Research Centre, INSIGHT Research Institute, Faculty of Health, University of Technology Sydney (UTS), Sydney, NSW, Australia.
Muna Al-KhaifiDepartment of Surgery, Mount Sinai Hospital, Toronto, Canada. muna.alkhaifi@sinaihealth.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCancer-related fatigue (CRF) is a persistent and distressing sense of physical, emotional, or cognitive exhaustion that results from cancer or its treatment, affecting approximately 70-100% of individuals diagnosed with cancer. Despite its prevalence and impact, CRF is often underrecognized and insufficiently managed. This review aims to provide healthcare providers with clear, evidence-based guidance to improve the recognition, assessment, and management of CRF across the continuum of cancer care.

methodsA narrative literature review was conducted by searching databases for peer-reviewed studies, clinical guidelines, and expert frameworks. Emphasis was placed on high-quality evidence supporting the recognition, assessment, and management of CRF in people with cancer.

resultsCRF may emerge before treatment, intensify during anti-cancer treatment, and persist long after treatment completion. It is multifactorial in origin and varies in severity and duration. Validated self-report tools such as the Numeric Rating Scale and EORTC QLQ-C30 are essential for accurate screening and assessment. Management should begin with addressing reversible contributors and proceed with individualized, multimodal interventions. Non-pharmacological approaches including structured physical activity, cognitive behavioral therapy, and mindfulness-based techniques have the strongest supporting evidence. Complementary strategies such as massage therapy, nutritional support, and bright light therapy also show potential benefit. Pharmacologic treatments remain limited in efficacy and should be considered only when non-pharmacologic options are insufficient.

conclusionsCRF is a clinically significant and potentially modifiable symptom that warrants routine assessment and personalized management. Integrating evidence-based screening tools and interventions into standard oncology care can improve patient outcomes and overall quality of life.

Indexed as

Cancer SurvivorsFatigueNeoplasmsHealth PersonnelHumansQuality of LifeCancer-related fatigueCancer survivorsPractice guidelineSurvivorship

Identifiers

PMID41706215

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.