Evidence map›Paper›PMID 41706175›Full record

ArticleOral and maxillofacial surgery2026

Antibacterial effect of banana leaf extract-coated sutures against oral pathogens and MRSA: an in vitro study.

Kadambari Vivek Kakde, Deepanjali Megarasu, Manikandhan Ramanathan

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Article in Oral and maxillofacial surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kadambari Vivek KakdeMeenakshi Ammal Dental College and Hospital, Meenakshi Academy of Higher Education and Research (Deemed to be University), Chennai, Tamil nadu, India.
Deepanjali MegarasuDepartment of Oral and Maxillofacial Surgery, Meenakshi Ammal Dental College and Hospital, Meenakshi Academy of Higher Education and Research (Deemed to be University), Chennai, Tamil nadu, India. drdeepanjali.da@gmail.com.ORCID http://orcid.org/0000-0001-5061-0577
Manikandhan RamanathanDepartment of Oral and Maxillofacial Surgery, Meenakshi Ammal Dental College and Hospital, Meenakshi Academy of Higher Education and Research (Deemed to be University), Chennai, Tamil nadu, India. drmaniramanathan@gmail.com.

Funding

Tamilnadu State Council For Science And Technology MS -251Tamilnadu State Council For Science And Technology MS-251
6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the efficacy of banana leaf extract as a novel antimicrobial coating for surgical sutures, with the primary goal of combating biofilm formation on suture surfaces—the key initiator of Surgical Site Infections (SSIs)—while inhibiting bacterial adhesion and colonization to reduce SSIs and enhance wound healing outcomes. MATERIAL AND

methodFresh banana leaves were processed using Soxhlet extraction to isolate bioactive compounds. Sterile non-absorbable sutures were coated with the extract at varying concentrations and tested against Staphylococcus aureus, Streptococcus mutans, Escherichia coli, Enterococcus faecalis and methicillin-resistant Staphylococcus aureus (MRSA) using agar diffusion and bacterial adhesion assays.

resultThe banana leaf extract-coated sutures demonstrated significant antibacterial activity against all strains, with zones of inhibition averaging 6.4 ± 1.2 mm (S. aureus), 7.1 ± 1.1 mm (MRSA), 15.8 ± 1.5 mm (S. mutans), 13.6 ± 1.0 mm (E. coli), and 14.3 ± 1.3 mm (E. faecalis) (p < 0.05 vs. controls by ANOVA/Tukey’s test); S. mutans showed the highest susceptibility. Bacterial adhesion and biofilm formation were significantly reduced on coated sutures compared to uncoated controls (p < 0.05).

conclusionThis study concludes that banana leaf extract-coated sutures exhibit broad-spectrum antimicrobial properties, effectively reducing bacterial growth and biofilm formation. This natural coating offers a promising alternative to synthetic antimicrobial agents, addressing concerns over antibiotic resistance and environmental impact.

Indexed as

Anti-Bacterial AgentsCoated Materials, BiocompatibleMethicillin-Resistant Staphylococcus aureusMusaPlant ExtractsPlant LeavesSuturesBacterial AdhesionBiofilmsEnterococcus faecalisEscherichia coliHumansIn Vitro TechniquesMicrobial Sensitivity TestsStaphylococcus aureusStreptococcus mutansAnti-Bacterial AgentsCoated Materials, BiocompatiblePlant ExtractsAntimicrobial coatingBacterial adhesionBanana leaf extractBiofilm formationMethicillin resistant staphylococcus aureusMRSASurgical site infections (SSIs)Surgical sutures

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.